TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Maryland Hospital
Curated by PDSP Ki Database
University Of Maryland Hospital
Curated by PDSP Ki Database
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Maryland Hospital
Curated by PDSP Ki Database
University Of Maryland Hospital
Curated by PDSP Ki Database
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Maryland Hospital
Curated by PDSP Ki Database
University Of Maryland Hospital
Curated by PDSP Ki Database
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Maryland Hospital
Curated by PDSP Ki Database
University Of Maryland Hospital
Curated by PDSP Ki Database
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataKi: 9.00E+3nMAssay Description:Inhibition of sheep placental cotyledons COX1More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Maryland Hospital
Curated by PDSP Ki Database
University Of Maryland Hospital
Curated by PDSP Ki Database
Affinity DataIC50: 99nMAssay Description:Inhibition of COX1 in human HEL 92.1.7 cells assessed as thromboxane B2 production incubated for 30 mins before arachidonic acid addition measured af...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Maryland Hospital
Curated by PDSP Ki Database
University Of Maryland Hospital
Curated by PDSP Ki Database
Affinity DataIC50: 290nMAssay Description:Inhibition of COX-1 in human washed platelet assessed as inhibition of 0.5 uM arachidonic acid-induced TXB2 formation incubated for 25 mins prior to ...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of COX in RBL1 cells assessed as reduction in PGE2/D2 production using A23187-induced arachidonic acid as substrate preincubated for 2 hrs...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: 1.06E+3nMAssay Description:Reverisible competitive inhibition of prostaglandin G/H synthase 1More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of ovine COX1 assessed as reduction in Prostaglandin production by enzyme immunoassayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Maryland Hospital
Curated by PDSP Ki Database
University Of Maryland Hospital
Curated by PDSP Ki Database
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of ovine COX1 by EIAMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Maryland Hospital
Curated by PDSP Ki Database
University Of Maryland Hospital
Curated by PDSP Ki Database
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of COX-1 in human washed platelet assessed as inhibition of 10 uM arachidonic acid-induced TXB2 formation incubated for 25 mins prior to a...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase in intact RBL-1 cell lineMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: 2.26E+3nMAssay Description:In vitro inhibitory concentration of the compound against ram seminal vescicle prostaglandin G/H synthase 1More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Maryland Hospital
Curated by PDSP Ki Database
University Of Maryland Hospital
Curated by PDSP Ki Database
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of sheep COX1 by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of bovine COX-1 by enzyme immuno assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of ovine COX1 by enzyme immunoassayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of ovine COX1 by enzyme immuno assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of ovine COX1 by enzyme immuno assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of ovine COX1 by enzyme immuno assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of ovine COX1 by enzyme immuno assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of ovine COX1 by enzyme immunoassayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of ovine COX1 by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of bovine COX1 by enzyme immunoassayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of ovine COX1 by enzyme immuno assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:In vitro inhibitory concentration of the compound against COX-1 enzymeMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of ovine COX1 by enzyme immuno assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of ovine COX1 by enzyme immuno assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of ovine COX1 by enzyme immuno assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Maryland Hospital
Curated by PDSP Ki Database
University Of Maryland Hospital
Curated by PDSP Ki Database
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Maryland Hospital
Curated by PDSP Ki Database
University Of Maryland Hospital
Curated by PDSP Ki Database
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Maryland Hospital
Curated by PDSP Ki Database
University Of Maryland Hospital
Curated by PDSP Ki Database
Affinity DataIC50: 3.00E+3nMAssay Description:Concentration (in microM) to inhibit 50% of Prostaglandin G/H synthase 1 (COX-1) and is expressed in IC50.More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of sheep COX1 by spectrophotometryMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: 3.35E+3nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of ovine COX-1More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMpH: 8.0Assay Description:Approximately 2 µg of either COX-1 or COX-2 was added to buffer containing 100 µM AA, 0.1 M Tris-HCl buffer (pH 8.0), 5 mM EDTA, 2 mM phenol, and 1 µ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of ovine COX1 pre-incubated for 10 mins before arachidonic acid substrate addition by enzyme immunoassayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Maryland Hospital
Curated by PDSP Ki Database
University Of Maryland Hospital
Curated by PDSP Ki Database
Affinity DataIC50: 6.30E+3nMAssay Description:Compound was evaluated for inhibition of Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as reduction in PGE2 formation pre-incubated for 5 mins before arachidonic acid addition and measured...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Maryland Hospital
Curated by PDSP Ki Database
University Of Maryland Hospital
Curated by PDSP Ki Database
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of COX1 in human whole blood after 15 minsMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: 7.60E+3nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 1 from ovineMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Ovine COX-1 preincubated for 15 mins by fluorescence analysisMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of purified ovine COX1 pre-treated for 1 hr before 10-acetyl-3,7-dihydroxyphenoxazin substrate addition in absence of porcine liver estera...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Maryland Hospital
Curated by PDSP Ki Database
University Of Maryland Hospital
Curated by PDSP Ki Database
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition activity against recombinant human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of ovine COX-1 assessed as residual activity by measuring formation of 12-HHT from arachidonic acid by HPLC analysisMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Faculdade De Ci�Ncias E Tecnologia-Unl
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of ovine COX1 after 5 minsMore data for this Ligand-Target Pair