Found 17 Enz. Inhib. hit(s) for PDB: 1SA1 
Affinity DataKi: 2.18E+3nMAssay Description:Binding affinity against tubulin using [3H]colchicine as radioligandMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 350nMAssay Description:Inhibition of tubulin polymerization in porcine brainMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of pig brain tubulin polymerization after 30 mins by turbidimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of porcine brain tubulin polymerizationMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of pig brain tubulin polymerization after 30 mins by turbidimetry analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of pig tubulin polymerization determined after 45 mins at 37 degC by turbidimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of pig brain tubulin polymerization after 30 mins by turbidimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees CMore data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibition of tubulin polymerization.(ITP)More data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Binding affinity to pig brain tubulin at 10 uM after 15 mins relative to controlMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:In vitro activity assay using leishmania tarentolae and porcine brain tubulin.More data for this Ligand-Target Pair
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of porcine brain tubulin polymerization by GTP-induced assemblyMore data for this Ligand-Target Pair
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentrationMore data for this Ligand-Target Pair
Affinity DataIC50: 3.71E+3nMAssay Description:Competitive binding affinity to pig brain tubulin colchicine binding site after 1 hr by mass spectrophotometric analysis in presence of colchicineMore data for this Ligand-Target Pair
