Found 3 Enz. Inhib. hit(s) for PDB: 1TL3 TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
University Of Oxford
University Of Oxford
Affinity DataIC50: 630nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
3D Structure (crystal)TargetGag-Pol polyprotein [588-1127,L687I]/[588-1147,L687I](Human immunodeficiency virus type 1)
University Of Oxford
University Of Oxford
Affinity DataIC50: 1.96E+3nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
University Of Oxford
University Of Oxford
Affinity DataIC50: 2.50E+3nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
