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PDB code 2ORS

Compile Data Set for Download or QSAR

Identical Ligands in BindingDB

Found 1 hit Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric oxide synthase, inducible

  (342/385 = 89%)
(Homo sapiens (Human))
BDBM50207104
PNG
(2-(4-(1H-imidazol-1-yl)phenoxy)-4-(benzo[d][1,3]di...)
Show SMILES Cc1cc(Oc2ccc3OCOc3c2)nc(Oc2ccc(cc2)-n2ccnc2)n1
Show InChI InChI=1S/C21H16N4O4/c1-14-10-20(28-17-6-7-18-19(11-17)27-13-26-18)24-21(23-14)29-16-4-2-15(3-5-16)25-9-8-22-12-25/h2-12H,13H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
CHEMBL
DrugBank
PC cid
PC sid
PDB
UniChem

Similars

PDB
Article
PubMed
n/an/a 90n/an/an/an/an/an/a



Berlex Biosciences

Curated by ChEMBL


Assay Description
Inhibition of iNOS in human A172 cells after 18 to 24 hrs


Bioorg Med Chem Lett 17: 2505-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.018
BindingDB Entry DOI: 10.7270/Q2XG9QTP
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)

Search BindingMOAD for More Affinity Data:

* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
Identities from BLAST output