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Found 4 Enz. Inhib. hit(s) for PDB: 2Q55
TargetDimer of Gag-Pol polyprotein [491-589,Q496K](Human immunodeficiency virus type 1)
University Of Massachusetts Medical School

LigandPNGBDBM17832((2S)-N-[(2S,4S,5S)-4-hydroxy-5-{[(5S)-2-oxo-3-phen...)
Affinity DataKi:  2.04nM ΔG°:  -50.4kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease inhibitor activities were determined by the fluorescence resonance energy transfer (FRET) method. The energy transfer donor (EDANS) an...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [491-589,Q498K,D521N,V555I,N579D](Human immunodeficiency virus type 1)
University Of Massachusetts Medical School

LigandPNGBDBM17832((2S)-N-[(2S,4S,5S)-4-hydroxy-5-{[(5S)-2-oxo-3-phen...)
Affinity DataKi:  13.9nMAssay Description:HIV-1 protease inhibitor activities were determined by the fluorescence resonance energy transfer (FRET) method. The energy transfer donor (EDANS) an...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [491-589,Q498K,L501I,G539V,I545V,V555I,V573A](Human immunodeficiency virus type 1)
University Of Massachusetts Medical School

LigandPNGBDBM17832((2S)-N-[(2S,4S,5S)-4-hydroxy-5-{[(5S)-2-oxo-3-phen...)
Affinity DataKi:  175nMAssay Description:HIV-1 protease inhibitor activities were determined by the fluorescence resonance energy transfer (FRET) method. The energy transfer donor (EDANS) an...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [491-589,Q498K,L501I,V555I,A562V,G564S,I575V,L581M](Human immunodeficiency virus type 1)
University Of Massachusetts Medical School

LigandPNGBDBM17832((2S)-N-[(2S,4S,5S)-4-hydroxy-5-{[(5S)-2-oxo-3-phen...)
Affinity DataKi:  185nMAssay Description:HIV-1 protease inhibitor activities were determined by the fluorescence resonance energy transfer (FRET) method. The energy transfer donor (EDANS) an...More data for this Ligand-Target Pair