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Found 9 Enz. Inhib. hit(s) for PDB: 2XFJ
TargetBeta-secretase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50231682(CHEMBL251862 | N-((2S,3R)-4-((S)-1-(cyclohexylamin...)
Affinity DataIC50:  13nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50231682(CHEMBL251862 | N-((2S,3R)-4-((S)-1-(cyclohexylamin...)
Affinity DataIC50:  13nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50231682(CHEMBL251862 | N-((2S,3R)-4-((S)-1-(cyclohexylamin...)
Affinity DataIC50:  13nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50231682(CHEMBL251862 | N-((2S,3R)-4-((S)-1-(cyclohexylamin...)
Affinity DataIC50:  307nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-40 production by cell based assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50231682(CHEMBL251862 | N-((2S,3R)-4-((S)-1-(cyclohexylamin...)
Affinity DataIC50:  310nMAssay Description:Inhibition of BACE1 expressed in SHSY5Y cells assessed as reduction of amyloid beta 40 productionMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50231682(CHEMBL251862 | N-((2S,3R)-4-((S)-1-(cyclohexylamin...)
Affinity DataIC50:  310nMAssay Description:Inhibition of BACE1 assessed as beta amyloid 40 production by cell based assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50231682(CHEMBL251862 | N-((2S,3R)-4-((S)-1-(cyclohexylamin...)
Affinity DataIC50:  360nMAssay Description:Inhibition of BACE1 expressed in SHSY5Y cells assessed as reduction of amyloid beta 42 productionMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50231682(CHEMBL251862 | N-((2S,3R)-4-((S)-1-(cyclohexylamin...)
Affinity DataIC50:  360nMAssay Description:Inhibition of BACE1 assessed as beta amyloid 42 production by cell based assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50231682(CHEMBL251862 | N-((2S,3R)-4-((S)-1-(cyclohexylamin...)
Affinity DataIC50:  363nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-42 production by cell based assayMore data for this Ligand-Target Pair