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Found 2 Enz. Inhib. hit(s) for PDB: 2YK2
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research And Development

Curated by ChEMBL
LigandPNGBDBM50357461(CHEMBL1917723)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of human Hsp90beta after overnight incubation by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research And Development

Curated by ChEMBL
LigandPNGBDBM50357455(CHEMBL1917724)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair