Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) for PDB: 3E30
LigandPNGBDBM31423(ethylenediamine scaffold, 4)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of Rap1A geranylgeranylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
LigandPNGBDBM31423(ethylenediamine scaffold, 4)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of H-Ras-mediated farnesylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
LigandPNGBDBM31423(ethylenediamine scaffold, 4)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of human farnesyltransferase assessed as incorporation of [3H]FPP into H-Ras-CVLSMore data for this Ligand-Target Pair
LigandPNGBDBM31423(ethylenediamine scaffold, 4)
Affinity DataIC50:  3.70E+3nMpH: 7.7 T: 2°CAssay Description:In vitro inhibition assay of human PFT was done by measuring the incorporation of [3H] FPP (Amersham Biosciences, Piscataway, NJ) into wild type H-Ra...More data for this Ligand-Target Pair
LigandPNGBDBM31423(ethylenediamine scaffold, 4)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human geranylgeranyltransferase-1 assessed as incorporation of [3H]GGPP into H-Ras-CVLLMore data for this Ligand-Target Pair
LigandPNGBDBM50366477(CHEMBL69330)
Affinity DataKd:  2nMAssay Description:Binding affinity to FTase (unknown origin)More data for this Ligand-Target Pair