Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) for PDB: 3HDM
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50296003(4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic ...)
Affinity DataIC50:  40nMAssay Description:Inhibition of SGK1 by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50296003(4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic ...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of SGK1-mediated epithelial sodium channel activity in human M-1 cells assessed as short circuit current by whole cell electrophysiologica...More data for this Ligand-Target Pair