BindingDB PrimarySearch

Found 2 Enz. Inhib. hit(s) for PDB: 3KSQ

Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

BDBM50495911(CHEMBL601202)

IC50: 0.300nMAssay Description:Inhibition of FTase (unknown origin) assessed as transfer of [H3]farnesyl from [H3]farnesyl pyrophosphate to trichloroacetic acid-precipitable HaRas-...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

BDBM50366477(CHEMBL69330)

Kd: 2nMAssay Description:Binding affinity to FTase (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

Purchase ChEBI
CHEMBL KEGG MMDB PC cid PC sid PDB Similars

Details Article PubMed MMDB
PDB

3D Structure (crystal)