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Found 3 Enz. Inhib. hit(s) for PDB: 3VHV
TargetMineralocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50359640(CHEMBL1928872)
Affinity DataIC50:  510nMAssay Description:Displacement of [3H]aldosterone from cytosolic human MR expressed in HEK293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
TargetMineralocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50359640(CHEMBL1928872)
Affinity DataIC50:  510nMAssay Description:Displacement of [3H]-Aldosterone from human MR overexpressed in FreeStyle 293 cells incubated for 16 hrs by TopCount methodMore data for this Ligand-Target Pair
TargetMineralocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50359640(CHEMBL1928872)
Affinity DataIC50:  510nMAssay Description:Antagonist activity at mineralocorticoid receptorMore data for this Ligand-Target Pair