Found 2 Enz. Inhib. hit(s) for PDB: 4DEB TargetAurora kinase A(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
US Patent
H. Lee Moffitt Cancer Center And Research Institute
US Patent
Affinity DataIC50: 226nMAssay Description:The phosphorylation of L-Hse was monitored by coupling the formation of ADP with pyruvate kinase and lactate dehydrogenase (PK/LDH). The resulting ox...More data for this Ligand-Target Pair
3D Structure (crystal)TargetAurora kinase A(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
US Patent
H. Lee Moffitt Cancer Center And Research Institute
US Patent
Affinity DataIC50: 372nMpH: 7.4 T: 2°CAssay Description:Reactions were carried out at room temperature in 15 mM HEPES buffer (pH 7.4) containing 20 mM NaCl, 1 mM EGTA, 0.02% Tween 20, 10 mM MgCl2, 5% (v/v)...More data for this Ligand-Target Pair
