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Found 2 Enz. Inhib. hit(s) for PDB: 4JSG
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Northwestern University

US Patent
LigandPNGBDBM50438644(CHEMBL2414429 | US9732037, Compound 1)
Affinity DataKi:  60nMAssay Description:NOS inhibition assays of representative compounds 1-21 were undertaken, and the results are summarized in Table 1, below. All NOS isoforms were expre...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50438644(CHEMBL2414429 | US9732037, Compound 1)
Affinity DataKi:  60nMAssay Description:Inhibition of recombinant rat nNOS expressed in Escherichia coli using L-arginine as substrate assessed as formation of nitric oxide measured up to 6...More data for this Ligand-Target Pair