Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) for PDB: 4MDD
TargetGlucocorticoid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50110730(CHEMBL3605919)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]-dexamethasone from human glucocorticoid receptor expressed in HEK293 cells by scintillation counting based radioligand competiti...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50110730(CHEMBL3605919)
Affinity DataIC50:  2.80nMAssay Description:Antagonist activity against glucocorticoid receptor (unknown origin) expressed in HEK293 cells by GRE-dependent luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50110730(CHEMBL3605919)
Affinity DataIC50:  11nMAssay Description:Antagonist activity against glucocorticoid receptor in rat H4-IIE cells assessed as inhibition of dexamethasone-induced receptor transactivation pre-...More data for this Ligand-Target Pair