TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Affinity DataKi: 320nMAssay Description:Inhibition of human COX2 preincubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of purified mouse COX-2 assessed as inhibition of PGE2-G/PGD2-G formation preincubated for 3 mins before 2-AG substrate addition measured ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 107nMAssay Description:Inhibition of human COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of human COX2 mediated PGE2 production in IL-1-beta-induced human dermal fibroblast cellsMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of human COX2 mediated PGE2 production in human whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair