Compile Data Set for Download or QSAR
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Found 2 Enz. Inhib. hit(s) for PDB: 5DBM
TargetCREB-binding protein(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM349364((4R)-6-(1-tert-butylpyrazol-4- | US10206931, Examp...)
Affinity DataIC50:  456nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
TargetCREB-binding protein/Histone acetyltransferase p300(Homo sapiens (Human))
Jilin University

Curated by ChEMBL
LigandPNGBDBM349364((4R)-6-(1-tert-butylpyrazol-4- | US10206931, Examp...)
Affinity DataIC50:  470nMAssay Description:Inhibition of human His-FLAG tagged CBP/EP300 (1082 to 1197 residues) using H4-TetraAc-biotin peptide as substrate after 90 mins by AlphaLISA methodMore data for this Ligand-Target Pair