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Found 6 Enz. Inhib. hit(s) for PDB: 5P9F
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50388183(CHEMBL2057915)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of human BTK by enzymatic assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50388183(CHEMBL2057915)
Affinity DataIC50:  6nMAssay Description:Inhibition of BTK (unknown origin) by Lanthascreen methodMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50388183(CHEMBL2057915)
Affinity DataIC50:  14nMAssay Description:Inhibition of BTK (unknown origin) by Lanthascreen assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Mus musculus)
Genentech

Curated by ChEMBL
LigandPNGBDBM50388183(CHEMBL2057915)
Affinity DataIC50:  60nMAssay Description:Inhibition of BTK-mediated CD86 surface expression in Balb/c mouse splenocytes preincubated for 60 mins before F(ab')2 anti-mouse IgM measured after ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50388183(CHEMBL2057915)
Affinity DataEC50:  380nMAssay Description:Inhibition of BTK in human whole blood B-cells assessed as inhibition of both anti-IgD-stimulated CD69 expressionMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50388183(CHEMBL2057915)
Affinity DataEC50:  350nMAssay Description:Inhibition of BTK in human whole blood basophils assessed as inhibition of both anti-IgE-stimulated CD63 expressionMore data for this Ligand-Target Pair