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PDB code 5U4B

Compile Data Set for Download or QSAR

Identical Ligands in BindingDB

Found 1 hit Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transthyretin

  (127/127 = 100%)
(Homo sapiens (Human))
BDBM50241604
PNG
(CHEMBL4060726)
Show SMILES OC(=O)c1cccc(\C=C\c2ccc(O)cc2)c1
Show InChI InChI=1S/C15H12O3/c16-14-8-6-11(7-9-14)4-5-12-2-1-3-13(10-12)15(17)18/h1-10,16H,(H,17,18)/b5-4+
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PDB
Article
PubMed
n/an/an/a 1.80E+3n/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Competitive binding affinity to human wild type TTR expressed in Escherichia coli BL-21 assessed as equilibrium dissociation constant of second site ...


J Med Chem 60: 7820-7834 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00952
BindingDB Entry DOI: 10.7270/Q26W9D7Z
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)

Search BindingMOAD for More Affinity Data:

* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
Identities from BLAST output