Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) for PDB: 5VO6
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50267826(CHEMBL4096145)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of JAK3 (unknown origin) using CSKtide as substrate after 30 mins in presence of [gamma33P]ATP by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetJAK3/JAK1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50267826(CHEMBL4096145)
Affinity DataIC50:  200nMAssay Description:Inhibition of JAK1/JAK3 in human whole blood assessed as reduction in IL-2 induced IFN-gamma production after 18 hrs by ELISAMore data for this Ligand-Target Pair