Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) for PDB: 6BW2
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM50244141(CHEMBL4094135 | US10533010, Example I-32 | US11208...)
Affinity DataKi: <7nMAssay Description:Compound affinity was measured using a fluorescence polarization anisotropy competition assay. Anisotropy measurements were carried out in 384-well, ...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM50244141(CHEMBL4094135 | US10533010, Example I-32 | US11208...)
Affinity DataKi:  21nMAssay Description:Inhibition of FITC-Bak-BH3/FITC-Bim-BH3 binding to MCL1 (172 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 CodonPlus (DE3) RIL...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM50244141(CHEMBL4094135 | US10533010, Example I-32 | US11208...)
Affinity DataKi: <50nMAssay Description:Compound affinity was measured using a fluorescence polarization anisotropy competition assay. Anisotropy measurements were carried out in 384-well, ...More data for this Ligand-Target Pair