Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Found
1
Enz. Inhib. hit(s) for PDB:
6MD7
Target
Tyrosine-protein phosphatase non-receptor type 11
(Homo sapiens (Human))
Novartis
US Patent
Ligand
BDBM395990
(Tert-butyl ((1-(4-((4-methoxybenzyl)oxy)pyrimidin-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 181nM
Assay Description:
SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
US Patent
PDB
3D Structure (crystal)
Copy BDB DOI