Compile Data Set for Download or QSAR
maximum 50k data
Found 21 Enz. Inhib. hit(s) with all data for entry = 50009048
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50078088((S)-3-(2-tert-Butyl-4-hydroxymethyl-5-methyl-pheny...)
Affinity DataKi:  0.0900nMpH: 4.7Assay Description:Inhibitory activity of the compound was evaluated against human immunodeficiency virus type 1(HIV-1) protease at pH 4.7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50216785(CHEMBL61756)
Affinity DataKi: <0.100nMpH: 4.7Assay Description:Inhibitory activity of the compound was evaluated against human immunodeficiency virus type 1(HIV-1) protease at pH 6.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50078088((S)-3-(2-tert-Butyl-4-hydroxymethyl-5-methyl-pheny...)
Affinity DataIC50:  1nMpH: 6.2Assay Description:Inhibitory activity of the compound was evaluated against human immunodeficiency virus type 1(HIV-1) protease at pH 6.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50216785(CHEMBL61756)
Affinity DataIC50: <1nMpH: 6.2Assay Description:Inhibitory concentration against human immunodeficiency virus type 1(HIV-1) protease at pH 4.7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50079704(3-(3-tert-Butyl-benzo[b]thiophen-2-ylsulfanyl)-4-h...)
Affinity DataIC50:  7nMpH: 4.7Assay Description:Inhibitory concentration against human immunodeficiency virus type 1(HIV-1) protease at pH 4.7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM2512(3-[(2-tert-butyl-5-methylphenyl)sulfanyl]-4-hydrox...)
Affinity DataIC50:  10nMpH: 4.7Assay Description:Inhibitory concentration against human immunodeficiency virus type 1(HIV-1) protease at pH 4.7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50079697(3-(3-tert-Butyl-benzofuran-2-ylsulfanyl)-4-hydroxy...)
Affinity DataIC50:  11nMpH: 4.7Assay Description:Inhibitory concentration against human immunodeficiency virus type 1(HIV-1) protease at pH 4.7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50079704(3-(3-tert-Butyl-benzo[b]thiophen-2-ylsulfanyl)-4-h...)
Affinity DataIC50:  17nMpH: 6.2Assay Description:Inhibitory concentration against human immunodeficiency virus type 1(HIV-1) protease at pH 4.7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50079702(3-(3-tert-Butyl-5,6,7,8-tetrahydro-naphthalen-2-yl...)
Affinity DataIC50:  28nMpH: 4.7Assay Description:Inhibitory concentration against human immunodeficiency virus type 1(HIV-1) protease at pH 4.7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50079707(3-(3-Ethyl-benzo[b]thiophen-2-ylsulfanyl)-4-hydrox...)
Affinity DataIC50:  28nMpH: 4.7Assay Description:Inhibitory concentration against human immunodeficiency virus type 1(HIV-1) protease at pH 4.7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM2512(3-[(2-tert-butyl-5-methylphenyl)sulfanyl]-4-hydrox...)
Affinity DataIC50:  35nMpH: 6.2Assay Description:Inhibitory activity of the compound was evaluated against human immunodeficiency virus type 1(HIV-1) protease at pH 6.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50079698(4-Hydroxy-3-(3-methyl-benzo[b]thiophen-2-ylsulfany...)
Affinity DataIC50:  74nMpH: 4.7Assay Description:Inhibitory concentration against human immunodeficiency virus type 1(HIV-1) protease at pH 4.7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50079701(3-(6-tert-Butyl-indan-5-ylsulfanyl)-4-hydroxy-6-ph...)
Affinity DataIC50:  130nMpH: 6.2Assay Description:Inhibitory activity of the compound was evaluated against human immunodeficiency virus type 1(HIV-1) protease at pH 6.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50079701(3-(6-tert-Butyl-indan-5-ylsulfanyl)-4-hydroxy-6-ph...)
Affinity DataIC50:  130nMpH: 6.2Assay Description:Inhibitory activity of the compound was evaluated against human immunodeficiency virus type 1(HIV-1) protease at pH 6.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50079709(4-Hydroxy-3-(3-methyl-thiophen-2-ylsulfanyl)-6-phe...)
Affinity DataIC50:  195nMpH: 4.7Assay Description:Inhibitory concentration against human immunodeficiency virus type 1(HIV-1) protease at pH 4.7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50079697(3-(3-tert-Butyl-benzofuran-2-ylsulfanyl)-4-hydroxy...)
Affinity DataIC50:  210nMpH: 6.2Assay Description:Inhibitory activity of the compound was evaluated against human immunodeficiency virus type 1(HIV-1) protease at pH 6.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50079705(3-(2-tert-Butyl-benzofuran-3-ylsulfanyl)-4-hydroxy...)
Affinity DataIC50:  211nMpH: 6.2Assay Description:Inhibitory concentration against human immunodeficiency virus type 1(HIV-1) protease at pH 4.7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50079705(3-(2-tert-Butyl-benzofuran-3-ylsulfanyl)-4-hydroxy...)
Affinity DataIC50:  211nMpH: 6.2Assay Description:Inhibitory activity of the compound was evaluated against human immunodeficiency virus type 1(HIV-1) protease at pH 6.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50079703(4-Hydroxy-6-phenethyl-6-phenyl-3-(thiophen-2-ylsul...)
Affinity DataIC50:  290nMpH: 4.7Assay Description:Inhibitory concentration against human immunodeficiency virus type 1(HIV-1) protease at pH 4.7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50079708(3-(Benzo[b]thiophen-2-ylsulfanyl)-4-hydroxy-6-phen...)
Affinity DataIC50:  363nMpH: 4.7Assay Description:Inhibitory concentration against human immunodeficiency virus type 1(HIV-1) protease at pH 4.7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50079699(3-(1-tert-Butyl-1H-benzoimidazol-2-ylsulfanyl)-4-h...)
Affinity DataIC50:  505nMpH: 4.7Assay Description:Inhibitory concentration against human immunodeficiency virus type 1(HIV-1) protease at pH 4.7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed