Compile Data Set for Download or QSAR
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Found 16 Enz. Inhib. hit(s) with all data for entry = 50009058
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079754(CHEMBL65476 | N*3*-Cyclopropyl-7-(4-isopropyl-benz...)
Affinity DataIC50:  52nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079751(CHEMBL63426 | N*3*-Cyclopropyl-7-(4-isopropyl-benz...)
Affinity DataIC50:  56nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079757(7-(4-Isopropyl-benzyl)-N*3*,N*3*-dimethyl-7H-pyrro...)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079755(7-(4-Isopropyl-benzyl)-3-piperidin-1-yl-7H-pyrrolo...)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079756(7-(4-Isopropyl-benzyl)-7H-pyrrolo[3,2-f]quinazolin...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079759(CHEMBL305557 | N*3*-Ethyl-7-(4-isopropyl-benzyl)-7...)
Affinity DataIC50:  524nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079753(7-(4-Isopropyl-benzyl)-N*3*-methyl-7H-pyrrolo[3,2-...)
Affinity DataIC50:  870nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079749(7-(4-tert-Butyl-benzyl)-7H-pyrrolo[3,2-f]quinazoli...)
Affinity DataIC50:  1.23E+3nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079764(7-(4-Isopropyl-benzyl)-N*1*,N*1*,N*3*,N*3*-tetrame...)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079758(7-(6-Methyl-naphthalen-2-ylmethyl)-7H-pyrrolo[3,2-...)
Affinity DataIC50:  1.75E+3nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079762(7-(4-Ethoxy-benzyl)-7H-pyrrolo[3,2-f]quinazoline-1...)
Affinity DataIC50:  2.63E+3nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079763(7-(4-Isopropyl-benzyl)-N*1*,N*3*,N*3*-trimethyl-7H...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079752(7-(4-Ethyl-benzyl)-7H-pyrrolo[3,2-f]quinazoline-1,...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079761(2-[1-Amino-7-(4-isopropyl-benzyl)-7H-pyrrolo[3,2-f...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079760(7-(4-Methylsulfanyl-benzyl)-7H-pyrrolo[3,2-f]quina...)
Affinity DataIC50:  6.88E+3nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079750(7-(4-Vinyl-benzyl)-7H-pyrrolo[3,2-f]quinazoline-1,...)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed