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Found 59 Enz. Inhib. hit(s) with all data for entry = 50009082
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079941((8-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079939((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi:  1.60nMAssay Description:The compound was tested for binding affinity against human Dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity of the compound to the dopamine receptor D2L in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079945((2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1-(2,3-...)
Affinity DataKi:  3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079950(CHEMBL430698 | N-(2,3-Dihydro-benzo[1,4]dioxin-2-y...)
Affinity DataKi:  3.10nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079939((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi:  3.60nMAssay Description:The compound was tested for binding affinity against 5-hydroxytryptamine 1A receptor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001885((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...)
Affinity DataKi:  5.10nMAssay Description:Binding affinity of the compound to the dopamine receptor D2L in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079940(CHEMBL324076 | [1-(2,3-Dihydro-benzo[1,4]dioxin-2-...)
Affinity DataKi:  6.90nMAssay Description:Binding affinity of the compound to the dopamine receptor D2L in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079940(CHEMBL324076 | [1-(2,3-Dihydro-benzo[1,4]dioxin-2-...)
Affinity DataKi:  6.90nMAssay Description:Binding affinity of the compound to the dopamine receptor D2L in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079947((2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1-(3-me...)
Affinity DataKi:  7nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079939((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi:  13.2nMAssay Description:The compound was tested for binding affinity against human Dopamine receptor D2LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079955((2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1-(4-me...)
Affinity DataKi:  15nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM35254(2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...)
Affinity DataKi:  15.7nMAssay Description:Binding affinity of the compound to the dopamine receptor D2L in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079950(CHEMBL430698 | N-(2,3-Dihydro-benzo[1,4]dioxin-2-y...)
Affinity DataKi:  16nMAssay Description:Binding affinity of the compound to the dopamine receptor D2L in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079951((8-Fluoro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi:  16nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079952(CHEMBL112526 | [1-(2-Chloro-phenyl)-piperidin-4-yl...)
Affinity DataKi:  17nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079946((2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1-(2,3-...)
Affinity DataKi:  18nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079944(CHEMBL114852 | [1-(2,3-Dihydro-benzo[1,4]dioxin-2-...)
Affinity DataKi:  20nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079940(CHEMBL324076 | [1-(2,3-Dihydro-benzo[1,4]dioxin-2-...)
Affinity DataKi:  21nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079940(CHEMBL324076 | [1-(2,3-Dihydro-benzo[1,4]dioxin-2-...)
Affinity DataKi:  21nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079939((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi:  22nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079946((2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1-(2,3-...)
Affinity DataKi:  23nMAssay Description:Binding affinity of the compound to the dopamine receptor D2L in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079953(3-({[1-(2-Methoxy-phenyl)-piperidin-4-ylmethyl]-am...)
Affinity DataKi:  25nMAssay Description:Binding affinity of the compound to the dopamine receptor D2L in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079939((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi:  27nMAssay Description:The compound was tested for binding affinity against 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079938((2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-(3,4,5,6...)
Affinity DataKi:  27nMAssay Description:Binding affinity of the compound to the dopamine receptor D2L in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079938((2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-(3,4,5,6...)
Affinity DataKi:  27nMAssay Description:Binding affinity of the compound to the dopamine receptor D2L in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079951((8-Fluoro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi:  28nMAssay Description:Binding affinity of the compound to the dopamine receptor D2L in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079943((2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-(1-pheny...)
Affinity DataKi:  29nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079952(CHEMBL112526 | [1-(2-Chloro-phenyl)-piperidin-4-yl...)
Affinity DataKi:  30nMAssay Description:Binding affinity of the compound to the dopamine receptor D2L in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079945((2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1-(2,3-...)
Affinity DataKi:  31nMAssay Description:Binding affinity of the compound to the dopamine receptor D2L in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079955((2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1-(4-me...)
Affinity DataKi:  36nMAssay Description:Binding affinity of the compound to the dopamine receptor D2L in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079943((2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-(1-pheny...)
Affinity DataKi:  39nMAssay Description:Binding affinity of the compound to the dopamine receptor D2L in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079939((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi:  44nMAssay Description:Binding affinity of the compound to the dopamine receptor D2L in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079947((2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1-(3-me...)
Affinity DataKi:  54nMAssay Description:Binding affinity of the compound to the dopamine receptor D2L in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079939((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi:  58nMAssay Description:The compound was tested for binding affinity against 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079954((5-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl...)
Affinity DataKi:  64nMAssay Description:Binding affinity of the compound to the dopamine receptor D2L in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079944(CHEMBL114852 | [1-(2,3-Dihydro-benzo[1,4]dioxin-2-...)
Affinity DataKi:  69nMAssay Description:Binding affinity of the compound to the dopamine receptor D2L in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079939((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi:  70.9nMAssay Description:The compound was tested for binding affinity against Dopamine receptor D4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079941((8-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl...)
Affinity DataKi:  76nMAssay Description:Binding affinity of the compound to the dopamine receptor D2L in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079949((2-Methyl-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi:  97nMAssay Description:Binding affinity of the compound to the dopamine receptor D2L in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079948((3-Methyl-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi:  113nMAssay Description:Binding affinity of the compound to the dopamine receptor D2L in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079954((5-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl...)
Affinity DataKi:  128nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079949((2-Methyl-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi:  195nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079942((2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-methyl-(...)
Affinity DataKi:  260nMAssay Description:Binding affinity of the compound to the dopamine receptor D2L in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataKi:  359nMAssay Description:Binding affinity of the compound to the dopamine receptor D2L in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataKi:  415nMAssay Description:The compound was tested binding affinity against 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligand at 10e-6 M.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi: >500nMAssay Description:The compound was tested binding affinity against 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligand at 10e-6 M.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor [16-465](Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079939((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi: >500nMAssay Description:The compound was tested for binding affinity against alpha-2D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079948((3-Methyl-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi: >500nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM35254(2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...)
Affinity DataKi: >500nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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