Compile Data Set for Download or QSAR
maximum 50k data
Found 24 Enz. Inhib. hit(s) with all data for entry = 50009099
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50080087(3-sec-Butoxy-4-(4-methanesulfonyl-phenyl)-5,5-dime...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50080083(3-Cyclohexyloxy-4-(4-methanesulfonyl-phenyl)-5,5-d...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50080080(3-(1-Cyclopropyl-ethoxy)-4-(4-methanesulfonyl-phen...)
Affinity DataIC50:  80nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50080082(3-Cyclopropylmethoxy-4-(4-methanesulfonyl-phenyl)-...)
Affinity DataIC50:  140nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50080081(3-Isopropoxy-4-(4-methanesulfonyl-phenyl)-5,5-dime...)
Affinity DataIC50:  300nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  400nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM22369(4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...)
Affinity DataIC50:  500nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50080088(3-Cyclopropoxy-4-(4-methanesulfonyl-phenyl)-5,5-di...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50080080(3-(1-Cyclopropyl-ethoxy)-4-(4-methanesulfonyl-phen...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibitory activity against Human Cyclooxygenase-1 ( COX-1 ) in U937 Microsome COX-1 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50080087(3-sec-Butoxy-4-(4-methanesulfonyl-phenyl)-5,5-dime...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM22369(4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50080084(3-Ethoxy-4-(4-methanesulfonyl-phenyl)-5,5-dimethyl...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50080082(3-Cyclopropylmethoxy-4-(4-methanesulfonyl-phenyl)-...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibitory activity against Human Prostaglandin G/H synthase 1 in U937 Microsome COX-1 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50080089(3-Cyclobutoxy-4-(4-methanesulfonyl-phenyl)-5,5-dim...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50080086(4-(4-Methanesulfonyl-phenyl)-3-methoxy-5,5-dimethy...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50080080(3-(1-Cyclopropyl-ethoxy)-4-(4-methanesulfonyl-phen...)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50080090(3-(1-Ethyl-propoxy)-4-(4-methanesulfonyl-phenyl)-5...)
Affinity DataIC50:  3.90E+4nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50080083(3-Cyclohexyloxy-4-(4-methanesulfonyl-phenyl)-5,5-d...)
Affinity DataIC50: >5.80E+4nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 1 in human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50080085(3-Cyclopentyloxy-4-(4-methanesulfonyl-phenyl)-5,5-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50080081(3-Isopropoxy-4-(4-methanesulfonyl-phenyl)-5,5-dime...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50080082(3-Cyclopropylmethoxy-4-(4-methanesulfonyl-phenyl)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed