Compile Data Set for Download or QSAR
maximum 50k data
Found 36 Enz. Inhib. hit(s) with all data for entry = 50009268
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081743(1-[4-(1H-Imidazol-4-yl)-but-3-ynyl]-4-(4-methyl-be...)
Affinity DataIC50:  20nMAssay Description:Inhibition of NMDA response at NR1A/2B receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081749(4-(4-Chloro-benzyl)-1-[4-(1H-imidazol-4-yl)-but-3-...)
Affinity DataIC50:  28nMAssay Description:Inhibition of NMDA response at NR1A/2B receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081748(4-Benzyl-1-[4-(1H-imidazol-4-yl)-but-3-ynyl]-piper...)
Affinity DataIC50:  37nMAssay Description:Inhibition of NMDA response at NR1A/2B receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081753(4-(4-Fluoro-benzyl)-1-[4-(1H-imidazol-4-yl)-but-3-...)
Affinity DataIC50:  50nMAssay Description:Inhibition of NMDA response at NR1A/2B receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081747(4-Benzyl-1-[4-(1H-pyrazol-4-yl)-but-3-ynyl]-piperi...)
Affinity DataIC50:  74nMAssay Description:Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081751(4-Benzyl-1-[3-(1H-imidazol-4-yl)-prop-2-ynyl]-pipe...)
Affinity DataIC50:  120nMAssay Description:Inhibition of NMDA response at NR1A/2B receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081745(4-Benzyl-1-[4-(1H-pyrrol-3-yl)-but-3-ynyl]-piperid...)
Affinity DataIC50:  190nMAssay Description:Inhibition of NMDA response at NR1A/2B receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081742(4-Benzyl-1-[4-(1H-imidazol-4-yl)-but-3-ynyl]-piper...)
Affinity DataIC50:  220nMAssay Description:Inhibition of NMDA response at NR1A/2B receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081746(1-[4-(1H-Imidazol-4-yl)-but-3-ynyl]-4-phenyl-piper...)
Affinity DataIC50:  810nMAssay Description:Inhibition of NMDA response at NR1A/2B receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 3A(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081744(4-Benzyl-1-[3-(1H-pyrazol-4-yl)-prop-2-ynyl]-piper...)
Affinity DataIC50:  820nMAssay Description:The compound was tested in vitro for activity against NR1A/2B sub type of NMDA receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081752(4-Benzyl-1-[3-(1H-pyrrol-3-yl)-prop-2-ynyl]-piperi...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of NMDA response at NR1A/2B receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 3A(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081746(1-[4-(1H-Imidazol-4-yl)-but-3-ynyl]-4-phenyl-piper...)
Affinity DataIC50:  1.40E+3nMAssay Description:Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081750(1-[4-(1H-Imidazol-4-yl)-but-3-ynyl]-4-phenyl-piper...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of NMDA response at NR1A/2B receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081746(1-[4-(1H-Imidazol-4-yl)-but-3-ynyl]-4-phenyl-piper...)
Affinity DataIC50:  5.00E+3nMAssay Description:Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2C receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 3A(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081750(1-[4-(1H-Imidazol-4-yl)-but-3-ynyl]-4-phenyl-piper...)
Affinity DataIC50:  8.40E+3nMAssay Description:Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 3A(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081743(1-[4-(1H-Imidazol-4-yl)-but-3-ynyl]-4-(4-methyl-be...)
Affinity DataIC50:  1.60E+4nMAssay Description:Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 3A(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081749(4-(4-Chloro-benzyl)-1-[4-(1H-imidazol-4-yl)-but-3-...)
Affinity DataIC50:  2.60E+4nMAssay Description:Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081751(4-Benzyl-1-[3-(1H-imidazol-4-yl)-prop-2-ynyl]-pipe...)
Affinity DataIC50:  3.40E+4nMAssay Description:Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2C receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081750(1-[4-(1H-Imidazol-4-yl)-but-3-ynyl]-4-phenyl-piper...)
Affinity DataIC50:  3.60E+4nMAssay Description:Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2C receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081743(1-[4-(1H-Imidazol-4-yl)-but-3-ynyl]-4-(4-methyl-be...)
Affinity DataIC50:  3.80E+4nMAssay Description:Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2C receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 3A(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081751(4-Benzyl-1-[3-(1H-imidazol-4-yl)-prop-2-ynyl]-pipe...)
Affinity DataIC50:  3.80E+4nMAssay Description:Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 3A(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081753(4-(4-Fluoro-benzyl)-1-[4-(1H-imidazol-4-yl)-but-3-...)
Affinity DataIC50:  4.00E+4nMAssay Description:Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 3A(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081745(4-Benzyl-1-[4-(1H-pyrrol-3-yl)-but-3-ynyl]-piperid...)
Affinity DataIC50:  5.10E+4nMAssay Description:Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 3A(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081752(4-Benzyl-1-[3-(1H-pyrrol-3-yl)-prop-2-ynyl]-piperi...)
Affinity DataIC50:  5.30E+4nMAssay Description:Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 3A(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081748(4-Benzyl-1-[4-(1H-imidazol-4-yl)-but-3-ynyl]-piper...)
Affinity DataIC50:  5.30E+4nMAssay Description:Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081752(4-Benzyl-1-[3-(1H-pyrrol-3-yl)-prop-2-ynyl]-piperi...)
Affinity DataIC50:  5.60E+4nMAssay Description:Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2C receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 3A(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081747(4-Benzyl-1-[4-(1H-pyrazol-4-yl)-but-3-ynyl]-piperi...)
Affinity DataIC50:  6.70E+4nMAssay Description:Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081748(4-Benzyl-1-[4-(1H-imidazol-4-yl)-but-3-ynyl]-piper...)
Affinity DataIC50:  7.00E+4nMAssay Description:Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2C receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081749(4-(4-Chloro-benzyl)-1-[4-(1H-imidazol-4-yl)-but-3-...)
Affinity DataIC50:  8.00E+4nMAssay Description:Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2C receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081742(4-Benzyl-1-[4-(1H-imidazol-4-yl)-but-3-ynyl]-piper...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2C receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 3A(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081742(4-Benzyl-1-[4-(1H-imidazol-4-yl)-but-3-ynyl]-piper...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081753(4-(4-Fluoro-benzyl)-1-[4-(1H-imidazol-4-yl)-but-3-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2C receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081744(4-Benzyl-1-[3-(1H-pyrazol-4-yl)-prop-2-ynyl]-piper...)
Affinity DataIC50: >1.00E+5nMAssay Description:The compound was tested in vitro for activity against NR1A/2C sub type of NMDA receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081745(4-Benzyl-1-[4-(1H-pyrrol-3-yl)-but-3-ynyl]-piperid...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2C receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 3A(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081744(4-Benzyl-1-[3-(1H-pyrazol-4-yl)-prop-2-ynyl]-piper...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of NMDA response at NR1A/2B receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081747(4-Benzyl-1-[4-(1H-pyrazol-4-yl)-but-3-ynyl]-piperi...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2C receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed