Compile Data Set for Download or QSAR
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Found 11 Enz. Inhib. hit(s) with all data for entry = 50036910
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM16452((4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-...)
Affinity DataIC50:  36.4nMAssay Description:Inhibitory Activity against Human recombinant Aldose Reductase (wild type)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM16496(2-{3-[(4-bromo-2-fluorophenyl)methyl]-7-chloro-2,4...)
Affinity DataIC50:  42.4nMAssay Description:Inhibitory Activity against Human recombinant Aldose Reductase (wild type)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)
Affinity DataIC50:  47nMAssay Description:Inhibitory Activity against Human recombinant Aldose Reductase (wild type)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50010283(2,7-difluorospiro[9H-fluorene-9,4'-(tetrahydro-1'H...)
Affinity DataIC50:  54.7nMAssay Description:Inhibitory Activity against Human recombinant Aldose Reductase (wild type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50009777((ponalrestat)[3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3,...)
Affinity DataIC50:  66.5nMAssay Description:Inhibitory Activity against Human recombinant Aldose Reductase (wild type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50038843((4R)-2-(4-bromo-2-fluorobenzyl)-6-fluoro-1H,2'H,5'...)
Affinity DataIC50:  72.6nMAssay Description:Inhibitory Activity against Human recombinant Aldose Reductase (wild type)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50086037(6-fluoro-2-methyl-1H,2'H,5'H-spiro[isoquinoline-4,...)
Affinity DataIC50:  73.2nMAssay Description:Inhibitory Activity against Human recombinant Aldose Reductase (wild type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50086038(6-chloro-2-methyl-1H,2'H,5'H-spiro[isoquinoline-4,...)
Affinity DataIC50:  78.2nMAssay Description:Inhibitory Activity against Human recombinant Aldose Reductase (wild type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50038846(6-fluoro-2-(5-trifluoromethylbenzo[d][1,3]thiazol-...)
Affinity DataIC50:  144nMAssay Description:Inhibitory Activity against Human recombinant Aldose Reductase (wild type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50086039(CHEMBL10350 | [2-(4-Bromo-2-fluoro-benzyl)-6-fluor...)
Affinity DataIC50:  227nMAssay Description:Inhibitory Activity against Human recombinant Aldose Reductase (wild type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  919nMAssay Description:Inhibitory Activity against Human recombinant Aldose Reductase (wild type)More data for this Ligand-Target Pair