Compile Data Set for Download or QSAR
maximum 50k data
Found 64 Enz. Inhib. hit(s) with all data for entry = 50009713
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM21392(3-(2-aminoethyl)-1H-indole-5-carboxamide | 5-CT | ...)
Affinity DataKi:  0.0290nMAssay Description:Binding affinity against Rat 5-hydroxytryptamine 7 receptor using [3H]-5-HTMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087033((1R,5aR)-1-methoxy-1,6-dimethyl-1,5,5a,6,7,8-hexah...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-5-HT from over-expressed rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087029((1S,5aR)-1-methoxy-1,6-dimethyl-1,5,5a,6,7,8-hexah...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-5-HT from over-expressed rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50016777(((R)-8-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity was measured on cloned Human 5-hydroxytryptamine 1A receptor which is labeled by [3H]-8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087037(1-Ethoxy-1-ethyl-6-methyl-1,5,5a,6,7,8-hexahydro-6...)
Affinity DataKi:  1.84nMAssay Description:Binding affinity was measured on cloned human 5-hydroxytryptamine 1A receptor which is labeled by [3H]-8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087027(1-Ethoxy-1-ethyl-6-methyl-1,5,5a,6,7,8-hexahydro-6...)
Affinity DataKi:  3.05nMAssay Description:Displacement of [3H]-5-HT from over-expressed rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087025((1R,5aR)-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza...)
Affinity DataKi:  3.36nMAssay Description:Binding affinity against Rat 5-hydroxytryptamine 7 receptor using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087031((1S,5aR)-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza...)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]-5-HT from over-expressed rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087025((1R,5aR)-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza...)
Affinity DataKi:  5.05nMAssay Description:Binding affinity was measured on cloned Human 5-hydroxytryptamine 1A receptor which is labeled by [3H]-8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087030((1S,5aR)-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza...)
Affinity DataKi:  5.60nMAssay Description:Binding affinity against Rat 5-hydroxytryptamine 7 receptor using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087036(6-Methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]ac...)
Affinity DataKi:  6.90nMAssay Description:Binding affinity against Rat 5-hydroxytryptamine 7 receptor using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087033((1R,5aR)-1-methoxy-1,6-dimethyl-1,5,5a,6,7,8-hexah...)
Affinity DataKi:  7.10nMAssay Description:Displacement of [3H]-Raclopride from human Dopamine receptor D2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50016777(((R)-8-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  8.81nMAssay Description:Binding affinity against Rat 5-hydroxytryptamine 7 receptor using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087035((1R,5aR)-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-ben...)
Affinity DataKi:  13.4nMAssay Description:Displacement of [3H]-5-HT from over-expressed rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087028((1R,5aR)-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-ben...)
Affinity DataKi:  13.5nMAssay Description:Displacement of [3H]-5-HT from over-expressed rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50052867((R)-6,11-Dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[d...)
Affinity DataKi:  14.4nMAssay Description:Binding affinity was measured on cloned Human 5-hydroxytryptamine 1A receptor which is labeled by [3H]-8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087029((1S,5aR)-1-methoxy-1,6-dimethyl-1,5,5a,6,7,8-hexah...)
Affinity DataKi:  16.9nMAssay Description:Binding affinity was measured on cloned human 5-hydroxytryptamine 1A receptor which is labeled by [3H]-8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087033((1R,5aR)-1-methoxy-1,6-dimethyl-1,5,5a,6,7,8-hexah...)
Affinity DataKi:  17.3nMAssay Description:Binding affinity was measured on cloned human 5-hydroxytryptamine 1A receptor which is labeled by [3H]-8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087024((1S,5aR)-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-ben...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]-5-HT from over-expressed rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087027(1-Ethoxy-1-ethyl-6-methyl-1,5,5a,6,7,8-hexahydro-6...)
Affinity DataKi:  19.1nMAssay Description:Binding affinity was measured on cloned human 5-hydroxytryptamine 1A receptor which is labeled by [3H]-8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087025((1R,5aR)-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza...)
Affinity DataKi:  19.4nMAssay Description:Binding affinity of the compound was measured on cloned Human D2A Receptor which is labeled by [3H]-RacloprideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087028((1R,5aR)-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-ben...)
Affinity DataKi:  23.8nMAssay Description:Displacement of [3H]-Raclopride from human Dopamine receptor D2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087027(1-Ethoxy-1-ethyl-6-methyl-1,5,5a,6,7,8-hexahydro-6...)
Affinity DataKi:  24.5nMAssay Description:Displacement of [3H]-Raclopride from human Dopamine receptor D2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087037(1-Ethoxy-1-ethyl-6-methyl-1,5,5a,6,7,8-hexahydro-6...)
Affinity DataKi:  25.7nMAssay Description:Displacement of [3H]-5-HT from over-expressed rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087031((1S,5aR)-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza...)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]-Raclopride from human Dopamine receptor D2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087039((1R,5aR)-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza...)
Affinity DataKi:  27.7nMAssay Description:Displacement of [3H]-5-HT from over-expressed rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087028((1R,5aR)-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-ben...)
Affinity DataKi:  31nMAssay Description:Binding affinity was measured on cloned rat 5-hydroxytryptamine 1A receptor which is labeled by [3H]-8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087030((1S,5aR)-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza...)
Affinity DataKi:  31.1nMAssay Description:Binding affinity was measured on cloned Human 5-hydroxytryptamine 1A receptor which is labeled by [3H]-8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50052867((R)-6,11-Dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[d...)
Affinity DataKi:  38.3nMAssay Description:Binding affinity against Rat 5-hydroxytryptamine 7 receptor using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087030((1S,5aR)-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza...)
Affinity DataKi:  39.2nMAssay Description:Binding affinity of the compound was measured on cloned Human D2A Receptor which is labeled by [3H]-RacloprideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087036(6-Methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]ac...)
Affinity DataKi:  40.7nMAssay Description:Binding affinity was measured on cloned Human 5-hydroxytryptamine 1A receptor which is labeled by [3H]-8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Affinity DataKi:  41.6nMAssay Description:Binding affinity of the compound was measured on cloned Human D2A Receptor which is labeled by [3H]-RacloprideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087031((1S,5aR)-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza...)
Affinity DataKi:  61.5nMAssay Description:Binding affinity was measured on cloned rat 5-hydroxytryptamine 1A receptor which is labeled by [3H]-8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087037(1-Ethoxy-1-ethyl-6-methyl-1,5,5a,6,7,8-hexahydro-6...)
Affinity DataKi:  70.8nMAssay Description:Displacement of [3H]-Raclopride from human Dopamine receptor D2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087029((1S,5aR)-1-methoxy-1,6-dimethyl-1,5,5a,6,7,8-hexah...)
Affinity DataKi:  71nMAssay Description:Displacement of [3H]-Raclopride from human Dopamine receptor D2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50052865((R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]q...)
Affinity DataKi:  80nMAssay Description:Binding affinity was measured on cloned Human 5-hydroxytryptamine 1A receptor which is labeled by [3H]-8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087036(6-Methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]ac...)
Affinity DataKi:  83.2nMAssay Description:Binding affinity of the compound was measured on cloned Human D2A Receptor which is labeled by [3H]-RacloprideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50013019((S)-7-(dipropylamino)-4-fluoro-5,6,7,8-tetrahydron...)
Affinity DataKi:  87nMAssay Description:Binding affinity was measured on cloned Human 5-hydroxytryptamine 1A receptor which is labeled by [3H]-8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50052865((R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]q...)
Affinity DataKi:  88nMAssay Description:Binding affinity against Rat 5-hydroxytryptamine 7 receptor using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087034((1S,5aR)-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-ben...)
Affinity DataKi:  103nMAssay Description:Displacement of [3H]-5-HT from over-expressed rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087026(6-Methyl-5a,6,7,8-tetrahydro-5H-6-aza-benzo[mno]ac...)
Affinity DataKi:  140nMAssay Description:Binding affinity was measured on cloned rat 5-hydroxytryptamine 1A receptor which is labeled by [3H]-8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087035((1R,5aR)-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-ben...)
Affinity DataKi:  142nMAssay Description:Binding affinity was measured on cloned human 5-hydroxytryptamine 1A receptor which is labeled by [3H]-8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087039((1R,5aR)-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza...)
Affinity DataKi:  182nMAssay Description:Displacement of [3H]-Raclopride from human Dopamine receptor D2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Affinity DataKi:  188nMAssay Description:Binding affinity against Rat 5-hydroxytryptamine 7 receptor using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50052867((R)-6,11-Dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[d...)
Affinity DataKi:  201nMAssay Description:Binding affinity of the compound was measured on cloned Human D2A Receptor which is labeled by [3H]-RacloprideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087032(CHEMBL282375 | N-((1R,5aR)-6-methyl-1,5,5a,6,7,8-h...)
Affinity DataKi:  204nMAssay Description:Binding affinity was measured on cloned human 5-hydroxytryptamine 1A receptor which is labeled by [3H]-8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087034((1S,5aR)-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-ben...)
Affinity DataKi:  215nMAssay Description:Displacement of [3H]-Raclopride from human Dopamine receptor D2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087035((1R,5aR)-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-ben...)
Affinity DataKi:  261nMAssay Description:Displacement of [3H]-Raclopride from human Dopamine receptor D2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087026(6-Methyl-5a,6,7,8-tetrahydro-5H-6-aza-benzo[mno]ac...)
Affinity DataKi:  291nMAssay Description:Displacement of [3H]-5-HT from over-expressed rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Affinity DataKi:  296nMAssay Description:Binding affinity was measured on cloned Human 5-hydroxytryptamine 1A receptor which is labeled by [3H]-8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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