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Found 42 Enz. Inhib. hit(s) with all data for entry = 50009760
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087536(3-(3-Carbamimidoyl-phenyl)-isoxazole-4-carboxylic ...)
Affinity DataKi:  0.100nMAssay Description:Inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087533(3-(3-Carbamimidoyl-phenyl)-isoxazole-4-carboxylic ...)
Affinity DataKi:  0.150nMAssay Description:Inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Oryctolagus cuniculus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087533(3-(3-Carbamimidoyl-phenyl)-isoxazole-4-carboxylic ...)
Affinity DataKi:  0.400nMAssay Description:Inhibitory activity of the compound was tested against rabbit Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087540(3-(3-Carbamimidoyl-phenyl)-5-hydroxymethyl-isoxazo...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087538((4S,5S)-3-(3-Carbamimidoyl-phenyl)-5-methoxymethyl...)
Affinity DataKi:  0.550nMAssay Description:Inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087532(3-(3-Carbamimidoyl-phenyl)-5-methoxymethyl-isoxazo...)
Affinity DataKi:  0.630nMAssay Description:Inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Oryctolagus cuniculus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087538((4S,5S)-3-(3-Carbamimidoyl-phenyl)-5-methoxymethyl...)
Affinity DataKi:  0.640nMAssay Description:Inhibitory activity of the compound was tested against rabbit Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087535(3-(3-Carbamimidoyl-phenyl)-5-methoxymethyl-isoxazo...)
Affinity DataKi:  0.75nMAssay Description:Inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Oryctolagus cuniculus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079252(3-(3-Carbamimidoyl-phenyl)-5-methoxymethyl-4,5-dih...)
Affinity DataKi:  0.800nMAssay Description:Inhibitory activity of the compound was tested against rabbit Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079236(3-(3-Carbamimidoyl-phenyl)-5-tetrazol-1-ylmethyl-4...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087539((4S,5R)-3-(3-Carbamimidoyl-phenyl)-5-methyl-4,5-di...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087537((4S,5S)-3-(3-Carbamimidoyl-phenyl)-5-tetrazol-1-yl...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087528(5-Amino-3-(3-carbamimidoyl-phenyl)-isoxazole-4-car...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079252(3-(3-Carbamimidoyl-phenyl)-5-methoxymethyl-4,5-dih...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087534(3-(3-Carbamimidoyl-phenyl)-5-trifluoromethyl-isoxa...)
Affinity DataKi:  9.5nMAssay Description:Inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079247(3-(3-Carbamimidoyl-phenyl)-5-methyl-4,5-dihydro-is...)
Affinity DataKi:  11nMAssay Description:Inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087533(3-(3-Carbamimidoyl-phenyl)-isoxazole-4-carboxylic ...)
Affinity DataKi:  21nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
TargetSerine protease 1(Bos taurus (bovine))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087536(3-(3-Carbamimidoyl-phenyl)-isoxazole-4-carboxylic ...)
Affinity DataKi:  25nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087540(3-(3-Carbamimidoyl-phenyl)-5-hydroxymethyl-isoxazo...)
Affinity DataKi:  50nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079252(3-(3-Carbamimidoyl-phenyl)-5-methoxymethyl-4,5-dih...)
Affinity DataKi:  70nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087532(3-(3-Carbamimidoyl-phenyl)-5-methoxymethyl-isoxazo...)
Affinity DataKi:  76nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079236(3-(3-Carbamimidoyl-phenyl)-5-tetrazol-1-ylmethyl-4...)
Affinity DataKi:  91nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087539((4S,5R)-3-(3-Carbamimidoyl-phenyl)-5-methyl-4,5-di...)
Affinity DataKi:  110nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087528(5-Amino-3-(3-carbamimidoyl-phenyl)-isoxazole-4-car...)
Affinity DataKi:  117nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079247(3-(3-Carbamimidoyl-phenyl)-5-methyl-4,5-dihydro-is...)
Affinity DataKi:  120nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087537((4S,5S)-3-(3-Carbamimidoyl-phenyl)-5-tetrazol-1-yl...)
Affinity DataKi:  180nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087538((4S,5S)-3-(3-Carbamimidoyl-phenyl)-5-methoxymethyl...)
Affinity DataKi:  190nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087535(3-(3-Carbamimidoyl-phenyl)-5-methoxymethyl-isoxazo...)
Affinity DataKi:  200nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087534(3-(3-Carbamimidoyl-phenyl)-5-trifluoromethyl-isoxa...)
Affinity DataKi:  400nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087536(3-(3-Carbamimidoyl-phenyl)-isoxazole-4-carboxylic ...)
Affinity DataKi:  540nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079236(3-(3-Carbamimidoyl-phenyl)-5-tetrazol-1-ylmethyl-4...)
Affinity DataKi:  900nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087540(3-(3-Carbamimidoyl-phenyl)-5-hydroxymethyl-isoxazo...)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087533(3-(3-Carbamimidoyl-phenyl)-isoxazole-4-carboxylic ...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079252(3-(3-Carbamimidoyl-phenyl)-5-methoxymethyl-4,5-dih...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087532(3-(3-Carbamimidoyl-phenyl)-5-methoxymethyl-isoxazo...)
Affinity DataKi:  3.80E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087528(5-Amino-3-(3-carbamimidoyl-phenyl)-isoxazole-4-car...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087539((4S,5R)-3-(3-Carbamimidoyl-phenyl)-5-methyl-4,5-di...)
Affinity DataKi:  4.50E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087538((4S,5S)-3-(3-Carbamimidoyl-phenyl)-5-methoxymethyl...)
Affinity DataKi:  4.60E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087537((4S,5S)-3-(3-Carbamimidoyl-phenyl)-5-tetrazol-1-yl...)
Affinity DataKi:  5.70E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079247(3-(3-Carbamimidoyl-phenyl)-5-methyl-4,5-dihydro-is...)
Affinity DataKi:  5.80E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087534(3-(3-Carbamimidoyl-phenyl)-5-trifluoromethyl-isoxa...)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087535(3-(3-Carbamimidoyl-phenyl)-5-methoxymethyl-isoxazo...)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed