Compile Data Set for Download or QSAR
maximum 50k data
Found 43 Enz. Inhib. hit(s) with all data for entry = 50036921
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087713((1-Ethyl-propyl)-[3-(4-methoxy-2-methyl-phenyl)-2,...)
Affinity DataKi:  1nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor 1 (hCRF1) receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087706(CHEMBL265847 | Urotensin-1-sucker fish(NDDPPISIDLT...)
Affinity DataKi:  1.07nMAssay Description:Binding affinity of the receptor corticotropin releasing factor receptor with peptidic agonistsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087706(CHEMBL265847 | Urotensin-1-sucker fish(NDDPPISIDLT...)
Affinity DataKi:  1.26nMAssay Description:Binding affinity of the receptor h-CRF2-alpha with peptidic agonistsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087719(4-(5,7-Dichloro-2,3-dihydro-indol-1-yl)-1-(1-ethyl...)
Affinity DataKi:  1.30nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor 1 (hCRF1) receptors.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084875(8-(2,4-dichlorophenyl)-N-(1,3-dimethoxypropan-2-yl...)
Affinity DataKi:  1.70nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084875(8-(2,4-dichlorophenyl)-N-(1,3-dimethoxypropan-2-yl...)
Affinity DataKi:  1.80nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087709(CHEMBL263451 | lactum astressin(cyclo(30-33)-[D-Ph...)
Affinity DataKi:  2nMAssay Description:Binding affinity of the receptor corticotropin releasing factor receptor with peptidic agonistsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50369802(CHEMBL475903 | CP-154526-1)
Affinity DataKi:  2.70nMAssay Description:binding affinity for human CRF1 receptor in IMR32 neuroblastoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087711(CHEMBL429560 | Sauvagine-frog(QGPPISIDLSLELLRKMIEI...)
Affinity DataKi:  2.73nMAssay Description:Binding affinity of the receptor h-CRF2-alpha with peptidic agonistsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087707(CHEMBL295563 | [3-(2,4-Dimethoxy-phenyl)-2,5-dimet...)
Affinity DataKi:  2.80nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor 1 (hCRF1) receptors.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087702((2-Chloro-4,6-dimethyl-phenyl)-[1-(2-methoxy-1-met...)
Affinity DataKi:  3.30nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087703(CHEMBL427807 | Urocortin-human(DNPSLSIDLTFHLLRTLLE...)
Affinity DataKi:  3.60nMAssay Description:Binding affinity of the receptor h-CRF2-alpha with peptidic agonistsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074456(CHEMBL10504 | SC241 | [3-(2-Bromo-4-isopropyl-phen...)
Affinity DataKi:  3.70nMAssay Description:Compound was tested for the inhibition of binding of the radioligand, [125 I-Tyr0]-CRF to rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087703(CHEMBL427807 | Urocortin-human(DNPSLSIDLTFHLLRTLLE...)
Affinity DataKi:  3.76nMAssay Description:Binding affinity of the receptor corticotropin releasing factor receptor with peptidic agonistsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076905(3-(2-Bromo-4-isopropyl-phenyl)-7-diethylamino-5-me...)
Affinity DataKi:  4.10nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor 1 (hCRF1) receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087704(CHEMBL265635 | r/h-CRF(SEEPPISLDLTFHLLREVLEMARAEQL...)
Affinity DataKi:  4.43nMAssay Description:Binding affinity of the receptor corticotropin releasing factor receptor with peptidic agonistsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076619(9-(2-Bromo-4-isopropyl-phenyl)-6-(butyl-ethyl-amin...)
Affinity DataKi:  5nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor 1 (hCRF1) receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071234(Butyl-[3-(2,4-dichloro-phenyl)-2,5-dimethyl-pyrazo...)
Affinity DataKi:  5nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor 1 (hCRF1) receptors.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50369801(CHEMBL1790241)
Affinity DataKi:  7.16nMAssay Description:Binding affinity of the receptor corticotropin releasing factor receptor with peptidic agonistsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087711(CHEMBL429560 | Sauvagine-frog(QGPPISIDLSLELLRKMIEI...)
Affinity DataKi:  7.30nMAssay Description:Binding affinity of the receptor corticotropin releasing factor receptor with peptidic agonistsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076900(3-(2-Bromo-4-isopropyl-phenyl)-7-diethylamino-5-me...)
Affinity DataKi:  9.40nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor 1 (hCRF1) receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074411((2-Bromo-4,6-dimethoxy-phenyl)-(4,6-dimethyl-pyrim...)
Affinity DataKi:  12nMAssay Description:Inhibition of binding of the radioligand, [125 I-Tyr0]-CRF to rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087704(CHEMBL265635 | r/h-CRF(SEEPPISLDLTFHLLREVLEMARAEQL...)
Affinity DataKi:  12.2nMAssay Description:Binding affinity of the receptor h-CRF2-alpha with peptidic agonistsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087714(CHEMBL297886 | [3-(3,4-Dimethoxy-phenyl)-2,5-dimet...)
Affinity DataKi:  13.7nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor 1 (hCRF1) receptors.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074353((2-Bromo-4,6-dimethoxy-phenyl)-ethyl-(4-methyl-6-m...)
Affinity DataKi:  32nMAssay Description:Inhibition of binding of the radioligand, [125 I-Tyr0]-CRF to rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074372((2-Bromo-4-isopropyl-phenyl)-ethyl-(4-methyl-6-mor...)
Affinity DataKi:  63nMAssay Description:Compound was tested for the inhibition of binding of the radioligand, [125 I-Tyr0]-CRF to rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50369801(CHEMBL1790241)
Affinity DataKi:  86.4nMAssay Description:Binding affinity of the receptor h-CRF2-alpha with peptidic agonistsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087707(CHEMBL295563 | [3-(2,4-Dimethoxy-phenyl)-2,5-dimet...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor receptor (hCRF2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087702((2-Chloro-4,6-dimethyl-phenyl)-[1-(2-methoxy-1-met...)
Affinity DataIC50:  75nMAssay Description:Inhibition of corticotropin releasing factor receptor mediated increase in cAMP level using HEK293 cells expressing h-CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087702((2-Chloro-4,6-dimethyl-phenyl)-[1-(2-methoxy-1-met...)
Affinity DataIC50:  79nMAssay Description:Inhibition of corticotropin releasing factor receptor mediated increase in cAMP level using rat cortical homogenates in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084875(8-(2,4-dichlorophenyl)-N-(1,3-dimethoxypropan-2-yl...)
Affinity DataIC50:  82nMAssay Description:Inhibition of corticotropin releasing factor receptor mediated increase in adenylate cyclase activity was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087711(CHEMBL429560 | Sauvagine-frog(QGPPISIDLSLELLRKMIEI...)
Affinity DataEC50:  3.40nMAssay Description:Activity of peptidic agonists on corticotropin releasing factor receptor receptor using agonist-stimulated adenylate cyclase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087703(CHEMBL427807 | Urocortin-human(DNPSLSIDLTFHLLRTLLE...)
Affinity DataEC50:  0.220nMAssay Description:Activity of peptidic agonists on corticotropin releasing factor receptor receptor using agonist-stimulated adenylate cyclase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087711(CHEMBL429560 | Sauvagine-frog(QGPPISIDLSLELLRKMIEI...)
Affinity DataEC50:  1.40nMAssay Description:Activity of peptidic agonists on h-CRF2-alpha receptor using agonist-stimulated adenylate cyclase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087706(CHEMBL265847 | Urotensin-1-sucker fish(NDDPPISIDLT...)
Affinity DataEC50:  6.30nMAssay Description:Activity of peptidic agonists on corticotropin releasing factor receptor receptor using agonist-stimulated adenylate cyclase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50369801(CHEMBL1790241)
Affinity DataEC50:  9.70nMAssay Description:Activity of peptidic agonists on corticotropin releasing factor receptor receptor using agonist-stimulated adenylate cyclase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087704(CHEMBL265635 | r/h-CRF(SEEPPISLDLTFHLLREVLEMARAEQL...)
Affinity DataEC50:  3.5nMAssay Description:Activity of peptidic agonists on corticotropin releasing factor receptor receptor using agonist-stimulated adenylate cyclase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087707(CHEMBL295563 | [3-(2,4-Dimethoxy-phenyl)-2,5-dimet...)
Affinity DataEC50:  142nMAssay Description:Antagonist potency in hCRF1 stimulated adenylate cyclase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087706(CHEMBL265847 | Urotensin-1-sucker fish(NDDPPISIDLT...)
Affinity DataEC50:  1.5nMAssay Description:Activity of peptidic agonists on h-CRF2-alpha receptor using agonist-stimulated adenylate cyclase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087703(CHEMBL427807 | Urocortin-human(DNPSLSIDLTFHLLRTLLE...)
Affinity DataEC50:  0.320nMAssay Description:Activity of peptidic agonists on h-CRF2-alpha receptor using agonist-stimulated adenylate cyclase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087704(CHEMBL265635 | r/h-CRF(SEEPPISLDLTFHLLREVLEMARAEQL...)
Affinity DataEC50:  13.2nMAssay Description:Activity of peptidic agonists on h-CRF2-alpha receptor using agonist-stimulated adenylate cyclase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50369801(CHEMBL1790241)
Affinity DataEC50:  61.9nMAssay Description:Activity of peptidic agonists on h-CRF2-alpha receptor using agonist-stimulated adenylate cyclase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087722(CHEMBL428505 | [D-Phe11,His12]Svg11-40(Antisauvagi...)
Affinity DataEC50:  3.76E+3nMAssay Description:Effective concentration to stimulate the human corticotropin releasing factor receptor using agonist-stimulated adenylate cyclase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed