TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor 1 (hCRF1) receptorsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.07nMAssay Description:Binding affinity of the receptor corticotropin releasing factor receptor with peptidic agonistsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.26nMAssay Description:Binding affinity of the receptor h-CRF2-alpha with peptidic agonistsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor 1 (hCRF1) receptors.More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor receptorMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor receptorMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Binding affinity of the receptor corticotropin releasing factor receptor with peptidic agonistsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:binding affinity for human CRF1 receptor in IMR32 neuroblastoma cellsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.73nMAssay Description:Binding affinity of the receptor h-CRF2-alpha with peptidic agonistsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.80nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor 1 (hCRF1) receptors.More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor receptorMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 3.60nMAssay Description:Binding affinity of the receptor h-CRF2-alpha with peptidic agonistsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 3.70nMAssay Description:Compound was tested for the inhibition of binding of the radioligand, [125 I-Tyr0]-CRF to rat cerebral cortex membraneMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 3.76nMAssay Description:Binding affinity of the receptor corticotropin releasing factor receptor with peptidic agonistsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 4.10nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor 1 (hCRF1) receptorsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 4.43nMAssay Description:Binding affinity of the receptor corticotropin releasing factor receptor with peptidic agonistsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor 1 (hCRF1) receptorsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor 1 (hCRF1) receptors.More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 7.16nMAssay Description:Binding affinity of the receptor corticotropin releasing factor receptor with peptidic agonistsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 7.30nMAssay Description:Binding affinity of the receptor corticotropin releasing factor receptor with peptidic agonistsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 9.40nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor 1 (hCRF1) receptorsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Inhibition of binding of the radioligand, [125 I-Tyr0]-CRF to rat cerebral cortex membraneMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 12.2nMAssay Description:Binding affinity of the receptor h-CRF2-alpha with peptidic agonistsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 13.7nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor 1 (hCRF1) receptors.More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 32nMAssay Description:Inhibition of binding of the radioligand, [125 I-Tyr0]-CRF to rat cerebral cortex membraneMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 63nMAssay Description:Compound was tested for the inhibition of binding of the radioligand, [125 I-Tyr0]-CRF to rat cerebral cortex membraneMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 86.4nMAssay Description:Binding affinity of the receptor h-CRF2-alpha with peptidic agonistsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor receptor (hCRF2)More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Inhibition of corticotropin releasing factor receptor mediated increase in cAMP level using HEK293 cells expressing h-CRF1 receptorMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of corticotropin releasing factor receptor mediated increase in cAMP level using rat cortical homogenates in vitro.More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 82nMAssay Description:Inhibition of corticotropin releasing factor receptor mediated increase in adenylate cyclase activity was evaluatedMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 3.40nMAssay Description:Activity of peptidic agonists on corticotropin releasing factor receptor receptor using agonist-stimulated adenylate cyclase assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 0.220nMAssay Description:Activity of peptidic agonists on corticotropin releasing factor receptor receptor using agonist-stimulated adenylate cyclase assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 1.40nMAssay Description:Activity of peptidic agonists on h-CRF2-alpha receptor using agonist-stimulated adenylate cyclase assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 6.30nMAssay Description:Activity of peptidic agonists on corticotropin releasing factor receptor receptor using agonist-stimulated adenylate cyclase assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 9.70nMAssay Description:Activity of peptidic agonists on corticotropin releasing factor receptor receptor using agonist-stimulated adenylate cyclase assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 3.5nMAssay Description:Activity of peptidic agonists on corticotropin releasing factor receptor receptor using agonist-stimulated adenylate cyclase assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 142nMAssay Description:Antagonist potency in hCRF1 stimulated adenylate cyclase assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 1.5nMAssay Description:Activity of peptidic agonists on h-CRF2-alpha receptor using agonist-stimulated adenylate cyclase assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 0.320nMAssay Description:Activity of peptidic agonists on h-CRF2-alpha receptor using agonist-stimulated adenylate cyclase assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 13.2nMAssay Description:Activity of peptidic agonists on h-CRF2-alpha receptor using agonist-stimulated adenylate cyclase assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 61.9nMAssay Description:Activity of peptidic agonists on h-CRF2-alpha receptor using agonist-stimulated adenylate cyclase assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 3.76E+3nMAssay Description:Effective concentration to stimulate the human corticotropin releasing factor receptor using agonist-stimulated adenylate cyclase assayMore data for this Ligand-Target Pair