Compile Data Set for Download or QSAR
maximum 50k data
Found 33 Enz. Inhib. hit(s) with all data for entry = 50009925
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089127(1-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-imidazol-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of murine p38 alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089122(1-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-imidazol-...)
Affinity DataIC50:  76nMAssay Description:Inhibition of murine p38 alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089123(1-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-imidazol-...)
Affinity DataIC50:  80nMAssay Description:Inhibition of murine p38 alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089125(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-imidazol-...)
Affinity DataIC50:  90nMAssay Description:Inhibition of murine p38 alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089130(1-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-imidazol-...)
Affinity DataIC50:  120nMAssay Description:Inhibition of murine p38 alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089124(4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-pyrrol-2-...)
Affinity DataIC50:  130nMAssay Description:Inhibition of murine p38 alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089132(1-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-imidazol-...)
Affinity DataIC50:  150nMAssay Description:Inhibition of murine p38 alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089122(1-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-imidazol-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of Prostaglandin G/H synthase 1, COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089126(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-oxazol-2-yl]...)
Affinity DataIC50:  350nMAssay Description:Inhibition of murine p38 alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089131(4-(2-tert-Butyl-5-phenyl-1H-imidazol-4-yl)-pyridin...)
Affinity DataIC50:  450nMAssay Description:Inhibition of murine p38 alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089128(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-thiazol-2-yl...)
Affinity DataIC50:  450nMAssay Description:Inhibition of murine p38 alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089133(2-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-imidazol-...)
Affinity DataIC50:  470nMAssay Description:Inhibition of murine p38 alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089126(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-oxazol-2-yl]...)
Affinity DataIC50:  797nMAssay Description:Inhibition of EGFR kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089129(4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-oxazol-2-yl]...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of murine p38 alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089126(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-oxazol-2-yl]...)
Affinity DataIC50:  2.41E+3nMAssay Description:Inhibition of human p38 beta MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089123(1-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-imidazol-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1, COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089131(4-(2-tert-Butyl-5-phenyl-1H-imidazol-4-yl)-pyridin...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1, COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089130(1-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-imidazol-...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1, COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089126(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-oxazol-2-yl]...)
Affinity DataIC50:  8.09E+3nMAssay Description:Inhibition of JNK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 13(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089126(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-oxazol-2-yl]...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human p38 delta MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089126(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-oxazol-2-yl]...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JNK1 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089126(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-oxazol-2-yl]...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ERK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089132(1-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-imidazol-...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1, COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089126(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-oxazol-2-yl]...)
Affinity DataIC50:  2.27E+4nMAssay Description:Inhibition of c-src kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089127(1-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-imidazol-...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1, COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Bos taurus (bovine))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089126(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-oxazol-2-yl]...)
Affinity DataIC50:  5.11E+4nMAssay Description:Inhibition of PKCalpha kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089128(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-thiazol-2-yl...)
Affinity DataIC50:  7.30E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1, COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Mus musculus)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089126(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-oxazol-2-yl]...)
Affinity DataIC50:  8.68E+4nMAssay Description:Inhibition of c-abl kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089133(2-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-imidazol-...)
Affinity DataIC50:  8.70E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1, COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089126(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-oxazol-2-yl]...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase 1, COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089124(4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-pyrrol-2-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase 1, COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089125(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-imidazol-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase 1, COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 6(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089126(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-oxazol-2-yl]...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MKK6b kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed