Compile Data Set for Download or QSAR
maximum 50k data
Found 19 Enz. Inhib. hit(s) with all data for entry = 50009935
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182((2R,4S)-4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrr...)
Affinity DataIC50:  7nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182((2R,4S)-4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrr...)
Affinity DataIC50:  39nMAssay Description:Inhibition of matrix metalloprotease -2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182((2R,4S)-4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrr...)
Affinity DataIC50:  82nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089187((2R,4S)-4-(4'-fluoro-1,1'-biphenyl-4-yl)-N-hydroxy...)
Affinity DataIC50:  182nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182((2R,4S)-4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrr...)
Affinity DataIC50:  703nMAssay Description:Inhibition of matrix metalloprotease -3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089185((2R,4S)-4-[4-(benzyloxy)phenyl]-N-hydroxy-5-oxopyr...)
Affinity DataIC50:  946nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089188((2R,4S)-N-hydroxy-4-(4-methoxyphenyl)-5-oxopyrroli...)
Affinity DataIC50:  1.48E+3nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182((2R,4S)-4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrr...)
Affinity DataIC50:  1.56E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089184(4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrrolidine-...)
Affinity DataIC50:  3.39E+3nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089186((2R,4S)-N-hydroxy-4-(2-naphthyl)-5-oxopyrrolidine-...)
Affinity DataIC50:  3.45E+3nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099471((2R,4S)-4-[3-(4-fluorophenoxy)phenyl]-N-hydroxy-5-...)
Affinity DataIC50:  4.76E+3nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089187((2R,4S)-4-(4'-fluoro-1,1'-biphenyl-4-yl)-N-hydroxy...)
Affinity DataIC50:  6.43E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089188((2R,4S)-N-hydroxy-4-(4-methoxyphenyl)-5-oxopyrroli...)
Affinity DataIC50:  8.04E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089183(4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrrolidine-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089183(4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrrolidine-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089185((2R,4S)-4-[4-(benzyloxy)phenyl]-N-hydroxy-5-oxopyr...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089184(4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrrolidine-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099471((2R,4S)-4-[3-(4-fluorophenoxy)phenyl]-N-hydroxy-5-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089186((2R,4S)-N-hydroxy-4-(2-naphthyl)-5-oxopyrrolidine-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed