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Found 15 Enz. Inhib. hit(s) with all data for entry = 50010064
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090529(2-[1-(Naphthalene-1-sulfonyl)-1H-indol-6-yl]-octah...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]-LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090527(1-(Naphthalene-1-sulfonyl)-6-(octahydro-indolizin-...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]-LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090527(1-(Naphthalene-1-sulfonyl)-6-(octahydro-indolizin-...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]-LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM28583(5-chloro-N-[4-methoxy-3-(piperazin-1-yl)phenyl]-3-...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090530(6-(1,2,3,5,8,8a-Hexahydro-indolizin-7-yl)-1-(napht...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090533(2-[1-(Naphthalene-1-sulfonyl)-1H-indol-6-yl]-octah...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]-LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090532(2-[1-(Naphthalene-2-sulfonyl)-1H-indol-6-yl]-octah...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090536(2-[1-(Toluene-4-sulfonyl)-1H-indol-6-yl]-octahydro...)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]-LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090535(2-[1-(2,4-Difluoro-benzenesulfonyl)-1H-indol-6-yl]...)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]-LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090531(7-[1-(Naphthalene-1-sulfonyl)-1H-indol-6-yl]-octah...)
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H]-LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090534(2-[1-(Toluene-4-sulfonyl)-1H-indol-6-yl]-octahydro...)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]-LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090526(2-(1-Benzenesulfonyl-1H-indol-6-yl)-octahydro-pyri...)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]-LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090524(4-Amino-N-(2,6-bis-methylamino-pyridin-4-yl)-benze...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]-LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090528(4-Amino-N-(2,6-bis-dimethylamino-pyrimidin-4-yl)-b...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]-LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090529(2-[1-(Naphthalene-1-sulfonyl)-1H-indol-6-yl]-octah...)
Affinity DataIC50:  7.20nMAssay Description:Antagonistic activity of the compound evaluated in adenylyl cyclase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed