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Found 28 Enz. Inhib. hit(s) with all data for entry = 50010470
TargetProthrombin(Homo sapiens (Human))
Lg Chemical

Curated by ChEMBL
LigandPNGBDBM50069294((S)-3-[4-(carbohydrazonamidol)-phenyl]-N-cyclopent...)
Affinity DataKi:  0.400nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Lg Chemical

Curated by ChEMBL
LigandPNGBDBM50095188(1-{3,3-diphenyl-(2R)-2-[(aminosulfonyl)amino]propa...)
Affinity DataKi:  0.800nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Lg Chemical

Curated by ChEMBL
LigandPNGBDBM50095190((S)-1-((R)-2-Methanesulfonylamino-3,3-diphenyl-pro...)
Affinity DataKi:  2.60nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Lg Chemical

Curated by ChEMBL
LigandPNGBDBM50095194((S)-1-((R)-3,3-Diphenyl-2-phenylmethanesulfonylami...)
Affinity DataKi:  3nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Lg Chemical

Curated by ChEMBL
LigandPNGBDBM50076722((S)-5-(4-Methylamino-phenyl)-2-(5,6,7,8-tetrahydro...)
Affinity DataKi:  5nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Lg Chemical

Curated by ChEMBL
LigandPNGBDBM50095198((S)-1-((R)-2-Amino-3,3-diphenyl-propionyl)-pyrroli...)
Affinity DataKi:  12nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Lg Chemical

Curated by ChEMBL
LigandPNGBDBM50095189(((R)-1-Benzhydryl-2-{(S)-2-[3-(1H-imidazol-4-yl)-p...)
Affinity DataKi:  14nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Lg Chemical

Curated by ChEMBL
LigandPNGBDBM50095190((S)-1-((R)-2-Methanesulfonylamino-3,3-diphenyl-pro...)
Affinity DataKi:  14nMAssay Description:Inhibitory activity of the compound against Bovine TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Lg Chemical

Curated by ChEMBL
LigandPNGBDBM50095191(((R)-1-Dicyclohexylmethyl-2-{(S)-2-[3-(1H-imidazol...)
Affinity DataKi:  15nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Lg Chemical

Curated by ChEMBL
LigandPNGBDBM50095188(1-{3,3-diphenyl-(2R)-2-[(aminosulfonyl)amino]propa...)
Affinity DataKi:  18nMAssay Description:Inhibitory activity of the compound against Bovine TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Lg Chemical

Curated by ChEMBL
LigandPNGBDBM50095189(((R)-1-Benzhydryl-2-{(S)-2-[3-(1H-imidazol-4-yl)-p...)
Affinity DataKi:  24nMAssay Description:Inhibitory activity of the compound against Bovine TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Lg Chemical

Curated by ChEMBL
LigandPNGBDBM50095194((S)-1-((R)-3,3-Diphenyl-2-phenylmethanesulfonylami...)
Affinity DataKi:  24nMAssay Description:Inhibitory activity of the compound against Bovine TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Lg Chemical

Curated by ChEMBL
LigandPNGBDBM50095193(((R)-1-Benzhydryl-2-{(S)-2-[3-(1H-imidazol-4-yl)-p...)
Affinity DataKi:  24nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Lg Chemical

Curated by ChEMBL
LigandPNGBDBM50095198((S)-1-((R)-2-Amino-3,3-diphenyl-propionyl)-pyrroli...)
Affinity DataKi:  25nMAssay Description:Inhibitory activity of the compound against Bovine TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Lg Chemical

Curated by ChEMBL
LigandPNGBDBM50095185(((R)-1-Dicyclohexylmethyl-2-{(S)-2-[3-(1H-imidazol...)
Affinity DataKi:  29nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Lg Chemical

Curated by ChEMBL
LigandPNGBDBM50095185(((R)-1-Dicyclohexylmethyl-2-{(S)-2-[3-(1H-imidazol...)
Affinity DataKi:  30nMAssay Description:Inhibitory activity of the compound against Bovine TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Lg Chemical

Curated by ChEMBL
LigandPNGBDBM50095191(((R)-1-Dicyclohexylmethyl-2-{(S)-2-[3-(1H-imidazol...)
Affinity DataKi:  30nMAssay Description:Inhibitory activity of the compound against Bovine TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Lg Chemical

Curated by ChEMBL
LigandPNGBDBM50069294((S)-3-[4-(carbohydrazonamidol)-phenyl]-N-cyclopent...)
Affinity DataKi:  33nMAssay Description:Inhibitory activity of the compound against Bovine TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Lg Chemical

Curated by ChEMBL
LigandPNGBDBM50095186(((R)-1-Benzhydryl-2-{(S)-2-[3-(1H-imidazol-4-yl)-p...)
Affinity DataKi:  44nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Lg Chemical

Curated by ChEMBL
LigandPNGBDBM50095186(((R)-1-Benzhydryl-2-{(S)-2-[3-(1H-imidazol-4-yl)-p...)
Affinity DataKi:  47nMAssay Description:Inhibitory activity of the compound against Bovine TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Lg Chemical

Curated by ChEMBL
LigandPNGBDBM50095193(((R)-1-Benzhydryl-2-{(S)-2-[3-(1H-imidazol-4-yl)-p...)
Affinity DataKi:  50nMAssay Description:Inhibitory activity of the compound against Bovine TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Lg Chemical

Curated by ChEMBL
LigandPNGBDBM50095200((S)-1-((R)-2-Acetylamino-3,3-diphenyl-propionyl)-p...)
Affinity DataKi:  208nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Lg Chemical

Curated by ChEMBL
LigandPNGBDBM50095195(((R)-1-Cyclohexylmethyl-2-{(S)-2-[3-(1H-imidazol-4...)
Affinity DataKi:  480nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Lg Chemical

Curated by ChEMBL
LigandPNGBDBM50095199(((R)-1-Benzyl-2-{(S)-2-[3-(1H-imidazol-4-yl)-prop-...)
Affinity DataKi:  1.20E+3nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Lg Chemical

Curated by ChEMBL
LigandPNGBDBM50095196(((R)-1-Benzyl-2-oxo-2-{(S)-2-[3-(1H-pyrazol-4-yl)-...)
Affinity DataKi:  5.40E+3nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Lg Chemical

Curated by ChEMBL
LigandPNGBDBM50095187((1-Benzyl-2-{2-[3-(3-methyl-3H-imidazol-4-yl)-prop...)
Affinity DataKi:  5.50E+3nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Lg Chemical

Curated by ChEMBL
LigandPNGBDBM50095192(((R)-2-{(S)-2-[3-(6-Amino-pyridin-3-yl)-prop-2-yny...)
Affinity DataKi: >2.00E+4nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Lg Chemical

Curated by ChEMBL
LigandPNGBDBM50095197(CHEMBL328360 | {(R)-1-Benzyl-2-oxo-2-[(S)-2-(3-pyr...)
Affinity DataKi: >2.00E+4nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed