Compile Data Set for Download or QSAR
maximum 50k data
Found 81 Enz. Inhib. hit(s) with all data for entry = 896
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6988(6-substituted quinazoline 38 | N-tert-butyl-6-(thi...)
Affinity DataIC50:  545nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM7001(6-(3-aminophenyl)-N-tert-butyl-2-(trifluoromethyl)...)
Affinity DataIC50:  600nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6995(4-[4-(tert-butylamino)-2-(trifluoromethyl)quinazol...)
Affinity DataIC50:  700nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6987(6-substituted quinazoline 37 | N-tert-butyl-2,6-bi...)
Affinity DataIC50:  790nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6986(6-substituted quinazoline 36 | N-[4-(tert-butylami...)
Affinity DataIC50:  925nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6997(3-[4-(tert-butylamino)-2-(trifluoromethyl)quinazol...)
Affinity DataIC50:  1.00E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6993(6-substituted quinazoline 43 | N-tert-butyl-6-(2-m...)
Affinity DataIC50:  1.00E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM7002(6-(4-aminophenyl)-N-tert-butyl-2-(trifluoromethyl)...)
Affinity DataIC50:  1.10E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM7002(6-(4-aminophenyl)-N-tert-butyl-2-(trifluoromethyl)...)
Affinity DataIC50: >1.10E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6985(4-(tert-butylamino)-2-(trifluoromethyl)quinazolin-...)
Affinity DataIC50:  1.15E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6990(6-substituted quinazoline 40 | N-tert-butyl-6-(thi...)
Affinity DataIC50:  1.18E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6989(6-substituted quinazoline 39 | N-tert-butyl-6-(fur...)
Affinity DataIC50:  1.20E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6991(6-substituted quinazoline 41 | N-tert-butyl-6-(pyr...)
Affinity DataIC50:  1.20E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6998(6-substituted quinazoline 48 | N-tert-butyl-6-[3-(...)
Affinity DataIC50:  1.20E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM7003(3-[4-(tert-butylamino)-2-(trifluoromethyl)quinazol...)
Affinity DataIC50:  1.30E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6972(4-substituted quinazoline 22 | N-(2-methylbutan-2-...)
Affinity DataIC50:  1.40E+3nMpH: 7.6 T: 2°CAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6964(2-substituted quinazoline 14 | N-tert-butyl-2-(tri...)
Affinity DataIC50:  1.50E+3nMpH: 7.6 T: 2°CAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6992(6-substituted quinazoline 42 | N-tert-butyl-6-phen...)
Affinity DataIC50:  1.80E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM7001(6-(3-aminophenyl)-N-tert-butyl-2-(trifluoromethyl)...)
Affinity DataIC50: >2.10E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6977(2-methyl-2-{[2-(trifluoromethyl)quinazolin-4-yl]am...)
Affinity DataIC50:  2.30E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM7000(6-substituted quinazoline 50 | N-tert-butyl-6-(2,4...)
Affinity DataIC50: >2.40E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM7003(3-[4-(tert-butylamino)-2-(trifluoromethyl)quinazol...)
Affinity DataIC50: >2.50E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6999(6-substituted quinazoline 49 | N-tert-butyl-6-(4-c...)
Affinity DataIC50:  2.60E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6993(6-substituted quinazoline 43 | N-tert-butyl-6-(2-m...)
Affinity DataIC50: >2.70E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6989(6-substituted quinazoline 39 | N-tert-butyl-6-(fur...)
Affinity DataIC50: >3.00E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6981(4-substituted quinazoline 31 | N-[(1R)-1-phenyleth...)
Affinity DataIC50:  3.20E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6996(6-substituted quinazoline 46 | N-tert-butyl-6-(3-m...)
Affinity DataIC50:  3.30E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6988(6-substituted quinazoline 38 | N-tert-butyl-6-(thi...)
Affinity DataIC50:  3.55E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6967(2-substituted quinazoline 17 | ethyl 4-(tert-butyl...)
Affinity DataIC50: >5.80E+3nMpH: 7.6 T: 2°CAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6963(2-substituted quinazoline 13 | N-tert-butyl-2-(tri...)
Affinity DataIC50:  6.10E+3nMpH: 7.6 T: 2°CAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6990(6-substituted quinazoline 40 | N-tert-butyl-6-(thi...)
Affinity DataIC50:  6.40E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6996(6-substituted quinazoline 46 | N-tert-butyl-6-(3-m...)
Affinity DataIC50: >6.70E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6980(4-substituted quinazoline 30 | N-(1-phenylethyl)-2...)
Affinity DataIC50:  6.80E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6992(6-substituted quinazoline 42 | N-tert-butyl-6-phen...)
Affinity DataIC50:  7.70E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6991(6-substituted quinazoline 41 | N-tert-butyl-6-(pyr...)
Affinity DataIC50:  8.30E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6998(6-substituted quinazoline 48 | N-tert-butyl-6-[3-(...)
Affinity DataIC50:  8.30E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6979(4-substituted quinazoline 29 | N-[(3,5-difluorophe...)
Affinity DataIC50:  8.90E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6994(6-substituted quinazoline 44 | N-tert-butyl-6-(4-m...)
Affinity DataIC50:  1.00E+4nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6995(4-[4-(tert-butylamino)-2-(trifluoromethyl)quinazol...)
Affinity DataIC50:  1.10E+4nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6963(2-substituted quinazoline 13 | N-tert-butyl-2-(tri...)
Affinity DataIC50:  1.19E+4nMpH: 7.6 T: 2°CAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6965(2-substituted quinazoline 15 | N-tert-butyl-2-(1,1...)
Affinity DataIC50:  1.19E+4nMpH: 7.6 T: 2°CAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6997(3-[4-(tert-butylamino)-2-(trifluoromethyl)quinazol...)
Affinity DataIC50:  1.20E+4nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM7000(6-substituted quinazoline 50 | N-tert-butyl-6-(2,4...)
Affinity DataIC50: >1.20E+4nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6986(6-substituted quinazoline 36 | N-[4-(tert-butylami...)
Affinity DataIC50:  1.40E+4nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6984(4-substituted quinazoline 34 | N-(2-phenylpropan-2...)
Affinity DataIC50:  1.40E+4nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6964(2-substituted quinazoline 14 | N-tert-butyl-2-(tri...)
Affinity DataIC50:  1.43E+4nMpH: 7.6 T: 2°CAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6976(4-substituted quinazoline 26 | {1-[2-(trifluoromet...)
Affinity DataIC50:  1.48E+4nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6977(2-methyl-2-{[2-(trifluoromethyl)quinazolin-4-yl]am...)
Affinity DataIC50:  1.50E+4nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6978(4-substituted quinazoline 28 | N-[(3-fluorophenyl)...)
Affinity DataIC50:  1.56E+4nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6983(4-substituted quinazoline 33 | N-[1-(4-fluoropheny...)
Affinity DataIC50:  1.65E+4nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 81 total ) | Next | Last >>
Jump to: