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Found 12 Enz. Inhib. hit(s) with all data for entry = 50036958
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pharmazeutisches Institut Der Universit£T Freiburg

Curated by ChEMBL
LigandPNGBDBM50346474((R)-4-[2-(3,4-Dichloro-phenyl)-acetyl]-3-pyrrolidi...)
Affinity DataKi:  0.450nMAssay Description:Affinity to opioid receptor kappa 1 using [3H]U-69593 as radioligand in homogenates of guinea pig brain membranesMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pharmazeutisches Institut Der Universit£T Freiburg

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataKi:  0.490nMAssay Description:Affinity to opioid receptor kappa 1 using [3H]U-69593 as radioligand in homogenates of guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Pharmazeutisches Institut Der Universit£T Freiburg

Curated by ChEMBL
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataKi:  0.680nMAssay Description:Affinity to mu-receptor, using [3H]DAMGO as radioligand in homogenates of guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pharmazeutisches Institut Der Universit£T Freiburg

Curated by ChEMBL
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataKi:  3.20nMAssay Description:Affinity to opioid receptor kappa 1 using [3H]U-69593 as radioligand in homogenates of guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pharmazeutisches Institut Der Universit£T Freiburg

Curated by ChEMBL
LigandPNGBDBM50102811(1-[4-Butyl-2-(1-pyrrolidin-1-yl-ethyl)-piperazin-1...)
Affinity DataKi:  134nMAssay Description:Affinity to opioid receptor kappa 1 using [3H]U-69593 as radioligand in homogenates of guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pharmazeutisches Institut Der Universit£T Freiburg

Curated by ChEMBL
LigandPNGBDBM50102806(1-[4-Butyl-2-(1-pyrrolidin-1-yl-ethyl)-piperazin-1...)
Affinity DataKi:  237nMAssay Description:Affinity to opioid receptor kappa 1 using [3H]U-69593 as radioligand in homogenates of guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Pharmazeutisches Institut Der Universit£T Freiburg

Curated by ChEMBL
LigandPNGBDBM50102811(1-[4-Butyl-2-(1-pyrrolidin-1-yl-ethyl)-piperazin-1...)
Affinity DataKi: >1.00E+3nMAssay Description:Affinity to mu-receptor, using [3H]DAMGO as radioligand in homogenates of guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Pharmazeutisches Institut Der Universit£T Freiburg

Curated by ChEMBL
LigandPNGBDBM50102806(1-[4-Butyl-2-(1-pyrrolidin-1-yl-ethyl)-piperazin-1...)
Affinity DataKi: >1.00E+3nMAssay Description:Affinity to mu-receptor, using [3H]DAMGO as radioligand in homogenates of guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pharmazeutisches Institut Der Universit£T Freiburg

Curated by ChEMBL
LigandPNGBDBM50102814(2-(3,4-Dichloro-phenyl)-1-[4-phenyl-2-(1-pyrrolidi...)
Affinity DataKi: >1.00E+3nMAssay Description:Affinity to opioid receptor kappa 1 using [3H]U-69593 as radioligand in homogenates of guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Pharmazeutisches Institut Der Universit£T Freiburg

Curated by ChEMBL
LigandPNGBDBM50102814(2-(3,4-Dichloro-phenyl)-1-[4-phenyl-2-(1-pyrrolidi...)
Affinity DataKi: >1.00E+3nMAssay Description:Affinity to mu-receptor, using [3H]DAMGO as radioligand in homogenates of guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Pharmazeutisches Institut Der Universit£T Freiburg

Curated by ChEMBL
LigandPNGBDBM50102813(2-(3,4-Dichloro-phenyl)-1-[4-phenyl-2-(1-pyrrolidi...)
Affinity DataKi: >1.00E+4nMAssay Description:Affinity to mu-receptor, using [3H]DAMGO as radioligand in homogenates of guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pharmazeutisches Institut Der Universit£T Freiburg

Curated by ChEMBL
LigandPNGBDBM50102813(2-(3,4-Dichloro-phenyl)-1-[4-phenyl-2-(1-pyrrolidi...)
Affinity DataKi: >1.00E+4nMAssay Description:Affinity to opioid receptor kappa 1 using [3H]U-69593 as radioligand in homogenates of guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed