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Found 16 Enz. Inhib. hit(s) with all data for entry = 50011288
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50104660(CHEMBL90820 | Naphthalene-2-sulfonic acid [3-(6-ch...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibitory concentration of the compound against trypanothione reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50104665(CHEMBL89368 | Naphthalene-2-sulfonic acid [4-(6-ch...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibitory concentration of the compound against trypanothione reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50104661(CHEMBL92155 | Naphthalene-2-sulfonic acid [2-(6-ch...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibitory concentration of the compound against trypanothione reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50104661(CHEMBL92155 | Naphthalene-2-sulfonic acid [2-(6-ch...)
Affinity DataIC50:  9.90E+3nMAssay Description:Inhibitory concentration of the compound against human Glutathione reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50104664(1-Benzyl-3-[6-(6-chloro-2-methoxy-acridin-9-ylamin...)
Affinity DataIC50:  1.14E+4nMAssay Description:Inhibitory concentration of the compound against trypanothione reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50104666(1-Benzyl-3-[3-(6-chloro-2-methoxy-acridin-9-ylamin...)
Affinity DataIC50:  1.31E+4nMAssay Description:Inhibitory concentration of the compound against trypanothione reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50104665(CHEMBL89368 | Naphthalene-2-sulfonic acid [4-(6-ch...)
Affinity DataIC50:  1.39E+4nMAssay Description:Inhibitory concentration of the compound against human Glutathione reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50104662(1-Benzyl-3-[4-(6-chloro-2-methoxy-acridin-9-ylamin...)
Affinity DataIC50:  1.55E+4nMAssay Description:Inhibitory concentration of the compound against trypanothione reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50104664(1-Benzyl-3-[6-(6-chloro-2-methoxy-acridin-9-ylamin...)
Affinity DataIC50:  1.71E+4nMAssay Description:Inhibitory concentration of the compound against human Glutathione reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50104663(1-Benzyl-3-[2-(6-chloro-2-methoxy-acridin-9-ylamin...)
Affinity DataIC50:  1.93E+4nMAssay Description:Inhibitory concentration of the compound against trypanothione reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50104663(1-Benzyl-3-[2-(6-chloro-2-methoxy-acridin-9-ylamin...)
Affinity DataIC50:  2.72E+4nMAssay Description:Inhibitory concentration of the compound against human Glutathione reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50104660(CHEMBL90820 | Naphthalene-2-sulfonic acid [3-(6-ch...)
Affinity DataIC50:  2.72E+4nMAssay Description:Inhibitory concentration of the compound against human Glutathione reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50104666(1-Benzyl-3-[3-(6-chloro-2-methoxy-acridin-9-ylamin...)
Affinity DataIC50:  4.47E+4nMAssay Description:Inhibitory concentration of the compound against human Glutathione reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50104662(1-Benzyl-3-[4-(6-chloro-2-methoxy-acridin-9-ylamin...)
Affinity DataIC50:  5.58E+4nMAssay Description:Inhibitory concentration of the compound against human Glutathione reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50015214(6-chloro-2-methoxy-9-acridinyl(4-diethylamino-1-me...)
Affinity DataIC50:  1.33E+5nMAssay Description:Inhibitory concentration of the compound against trypanothione reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50015214(6-chloro-2-methoxy-9-acridinyl(4-diethylamino-1-me...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory concentration of the compound against human Glutathione reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed