Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with all data for entry = 50011922
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112086(3-({2-[(4-Carbamimidoyl-phenylamino)-methyl]-1-met...)
Affinity DataKi:  4.5nMAssay Description:Inhibitory constant (Ki) was determined against human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1/Trypsin-2(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112086(3-({2-[(4-Carbamimidoyl-phenylamino)-methyl]-1-met...)
Affinity DataKi:  50.3nMAssay Description:Inhibitory constant (Ki) was determined against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112086(3-({2-[(4-Carbamimidoyl-phenylamino)-methyl]-1-met...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibitory constant (Ki) was determined against human plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112086(3-({2-[(4-Carbamimidoyl-phenylamino)-methyl]-1-met...)
Affinity DataKi:  3.76E+3nMAssay Description:Inhibitory constant (Ki) was determined against human Coagulation factor Xa (fXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112086(3-({2-[(4-Carbamimidoyl-phenylamino)-methyl]-1-met...)
Affinity DataKi:  2.09E+4nMAssay Description:Inhibitory constant (Ki) was determined against human Activated protein CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112086(3-({2-[(4-Carbamimidoyl-phenylamino)-methyl]-1-met...)
Affinity DataKi:  4.54E+4nMAssay Description:Inhibitory constant (Ki) was determined against human Tissue plasminogen activator (tissue plasminogen activator)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112083(3-({2-[(4-Carbamimidoyl-phenylamino)-methyl]-1-met...)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112086(3-({2-[(4-Carbamimidoyl-phenylamino)-methyl]-1-met...)
Affinity DataIC50:  9.30nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112087(({2-[(4-Carbamimidoyl-phenylamino)-methyl]-1-methy...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112080(4-({2-[(4-Carbamimidoyl-phenylamino)-methyl]-1-met...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112085(CHEMBL298500 | [{2-[(4-Carbamimidoyl-phenylamino)-...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112073(CHEMBL417360 | [{2-[2-(4-Carbamimidoyl-phenyl)-eth...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112095(({2-[2-(4-Carbamimidoyl-phenyl)-ethyl]-1-methyl-1H...)
Affinity DataIC50:  54nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112081(CHEMBL51528 | [[2-(4-Carbamimidoyl-phenoxymethyl)-...)
Affinity DataIC50:  58nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112093(CHEMBL46434 | [[2-(4-Carbamimidoyl-benzyl)-1-methy...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112079(4-[[2-(4-Carbamimidoyl-benzyl)-1-methyl-1H-benzoim...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50037996(1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimido...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112074(4-[1-Methyl-5-(quinoline-8-sulfonylamino)-1H-benzo...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112094(CHEMBL49216 | {[2-(4-Carbamimidoyl-phenoxymethyl)-...)
Affinity DataIC50:  330nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112077(4-[5-(Isoquinoline-5-sulfonylamino)-1-methyl-1H-be...)
Affinity DataIC50:  510nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112089(4-[1-Methyl-5-(naphthalene-1-sulfonylamino)-1H-ben...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112076(4-[5-(Benzenesulfonyl-methyl-amino)-1-methyl-1H-be...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112082(4-(5-Benzenesulfonylamino-1-methyl-1H-benzoimidazo...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112092(4-[1-Methyl-5-(pyridine-3-sulfonylamino)-1H-benzoi...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112075(4-[5-(2,5-Dimethoxy-benzenesulfonylamino)-1-methyl...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112091(4-(5-Benzenesulfonylamino-1-ethyl-1H-benzoimidazol...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112088(4-(5-Benzenesulfonylamino-1-propyl-1H-benzoimidazo...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112090(4-(5-Benzenesulfonylamino-1H-benzoimidazol-2-ylmet...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112078(4-[1-Methyl-5-(naphthalene-2-sulfonylamino)-1H-ben...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112084(4-[5-(3,5-Bis-trifluoromethyl-benzenesulfonylamino...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed