Compile Data Set for Download or QSAR
maximum 50k data
Found 29 Enz. Inhib. hit(s) with all data for entry = 50012205
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116031(3,5,6-Trifluoro-4-[4-(4-fluoro-phenyl)-5-pyridin-4...)
Affinity DataIC50:  4nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116037(3,5-Difluoro-4-[5-(4-fluoro-phenyl)-4-pyridin-4-yl...)
Affinity DataIC50:  4nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116038(4-(4-Benzofuran-2-yl-5-pyridin-4-yl-1H-imidazol-2-...)
Affinity DataIC50:  5nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116029(3,5-Difluoro-4-[4-(4-fluoro-phenyl)-5-pyridin-4-yl...)
Affinity DataIC50:  16nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116025(2,3,5,6-Tetrafluoro-4-[4-(4-fluoro-phenyl)-5-pyrid...)
Affinity DataIC50:  90nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116028(3,5-Difluoro-4-[4-(4-fluoro-phenyl)-5-pyridin-4-yl...)
Affinity DataIC50:  140nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116039(3,5-Difluoro-4-[4-(4-fluoro-phenyl)-5-pyridin-4-yl...)
Affinity DataIC50:  210nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116032(3,5-Difluoro-4-[4-(4-fluoro-phenyl)-5-pyridin-4-yl...)
Affinity DataIC50:  400nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116034(3,5-Difluoro-4-[5-pyridin-4-yl-4-(3-trifluoromethy...)
Affinity DataIC50:  470nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116027(3,5-Difluoro-4-(4-furan-2-yl-5-pyridin-4-yl-1H-imi...)
Affinity DataIC50:  670nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116033(2-(4-Fluorophenyl)-3-(pyridin-4-yl)-1H-pyrrole | 4...)
Affinity DataIC50:  800nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116024(4-[4-(4-Fluoro-phenyl)-thiazol-5-yl]-pyridine | CH...)
Affinity DataIC50:  800nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50053410(4-(4-Fluorophenyl)-5-(pyridin-4-yl)-1H-imidazole |...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116026(4-[5-(4-Fluoro-phenyl)-2H-[1,2,3]triazol-4-yl]-pyr...)
Affinity DataIC50:  1.30E+3nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116030(3,5,6-Trifluoro-4-[4-(4-fluoro-phenyl)-5-pyridin-4...)
Affinity DataIC50:  2.10E+3nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116037(3,5-Difluoro-4-[5-(4-fluoro-phenyl)-4-pyridin-4-yl...)
Affinity DataIC50:  6.30E+3nMAssay Description:In vivo inhibition of ram seminal vesicle Prostaglandin G/H synthase 1 activity by determining PGE-2 by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116035(2,3,5,6-Tetrafluoro-4-[4-(4-fluoro-phenyl)-5-pyrid...)
Affinity DataIC50:  1.00E+4nMAssay Description:In vivo inhibition of ram seminal vesicle Prostaglandin G/H synthase 1 activity by determining PGE-2 by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116035(2,3,5,6-Tetrafluoro-4-[4-(4-fluoro-phenyl)-5-pyrid...)
Affinity DataIC50:  1.00E+4nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116039(3,5-Difluoro-4-[4-(4-fluoro-phenyl)-5-pyridin-4-yl...)
Affinity DataIC50:  4.50E+4nMAssay Description:In vivo inhibition of ram seminal vesicle Prostaglandin G/H synthase 1 activity by determining PGE-2 by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116029(3,5-Difluoro-4-[4-(4-fluoro-phenyl)-5-pyridin-4-yl...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vivo inhibition of ram seminal vesicle Prostaglandin G/H synthase 1 activity by determining PGE-2 by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116027(3,5-Difluoro-4-(4-furan-2-yl-5-pyridin-4-yl-1H-imi...)
Affinity DataIC50:  1.00E+5nMAssay Description:In vivo inhibition of ram seminal vesicle Prostaglandin G/H synthase 1 activity by determining PGE-2 by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116030(3,5,6-Trifluoro-4-[4-(4-fluoro-phenyl)-5-pyridin-4...)
Affinity DataIC50:  1.00E+5nMAssay Description:In vivo inhibition of ram seminal vesicle Prostaglandin G/H synthase 1 activity by determining PGE-2 by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116032(3,5-Difluoro-4-[4-(4-fluoro-phenyl)-5-pyridin-4-yl...)
Affinity DataIC50:  1.00E+5nMAssay Description:In vivo inhibition of ram seminal vesicle Prostaglandin G/H synthase 1 activity by determining PGE-2 by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116038(4-(4-Benzofuran-2-yl-5-pyridin-4-yl-1H-imidazol-2-...)
Affinity DataIC50:  1.00E+5nMAssay Description:In vivo inhibition of ram seminal vesicle Prostaglandin G/H synthase 1 activity by determining PGE-2 by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116036(2,3,5,6-Tetrafluoro-4-[4-(4-fluoro-phenyl)-5-pyrid...)
Affinity DataIC50:  1.00E+5nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116034(3,5-Difluoro-4-[5-pyridin-4-yl-4-(3-trifluoromethy...)
Affinity DataIC50:  1.00E+5nMAssay Description:In vivo inhibition of ram seminal vesicle Prostaglandin G/H synthase 1 activity by determining PGE-2 by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116028(3,5-Difluoro-4-[4-(4-fluoro-phenyl)-5-pyridin-4-yl...)
Affinity DataIC50:  1.00E+5nMAssay Description:In vivo inhibition of ram seminal vesicle Prostaglandin G/H synthase 1 activity by determining PGE-2 by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116025(2,3,5,6-Tetrafluoro-4-[4-(4-fluoro-phenyl)-5-pyrid...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vivo inhibition of ram seminal vesicle Prostaglandin G/H synthase 1 activity by determining PGE-2 by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116031(3,5,6-Trifluoro-4-[4-(4-fluoro-phenyl)-5-pyridin-4...)
Affinity DataIC50:  1.00E+5nMAssay Description:In vivo inhibition of ram seminal vesicle Prostaglandin G/H synthase 1 activity by determining PGE-2 by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed