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Found 14 Enz. Inhib. hit(s) with all data for entry = 50035258
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM4779(CHEMBL31965 | CHEMBL545315 | CI-1033 | Canertinib ...)
Affinity DataIC50:  74nMAssay Description:Inhibition of Epidermal Growth Factor Receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50119074(CHEMBL95774 | N-[4-(3-Chloro-4-fluoro-phenylamino)...)
Affinity DataIC50:  80nMAssay Description:Inhibition of Epidermal Growth Factor Receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM31090((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...)
Affinity DataIC50:  83nMAssay Description:Inhibition of Epidermal Growth Factor Receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataIC50:  515nMAssay Description:Inhibition of Epidermal Growth Factor Receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM4779(CHEMBL31965 | CHEMBL545315 | CI-1033 | Canertinib ...)
Affinity DataIC50:  529nMAssay Description:Inhibition of human epidermal growth factor receptor-2 autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50119073(4-(3-Ethynyl-phenylamino)-6,7-bis-(2-methoxy-ethox...)
Affinity DataIC50:  850nMAssay Description:Inhibition of Epidermal Growth Factor Receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50119071(4-(3-Chloro-4-fluoro-phenylamino)-7-methoxy-6-(3-m...)
Affinity DataIC50:  1.04E+3nMAssay Description:Inhibition of Epidermal Growth Factor Receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM31090((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...)
Affinity DataIC50:  1.23E+3nMAssay Description:Inhibition of human epidermal growth factor receptor-2 autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  1.45E+3nMAssay Description:Inhibition of Epidermal Growth Factor Receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human epidermal growth factor receptor-2 autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50119074(CHEMBL95774 | N-[4-(3-Chloro-4-fluoro-phenylamino)...)
Affinity DataIC50:  1.69E+3nMAssay Description:Inhibition of human epidermal growth factor receptor-2 autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50119073(4-(3-Ethynyl-phenylamino)-6,7-bis-(2-methoxy-ethox...)
Affinity DataIC50:  1.18E+4nMAssay Description:Inhibition of human epidermal growth factor receptor-2 autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50119071(4-(3-Chloro-4-fluoro-phenylamino)-7-methoxy-6-(3-m...)
Affinity DataIC50:  1.47E+4nMAssay Description:Inhibition of human epidermal growth factor receptor-2 autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  1.85E+4nMAssay Description:Inhibition of human epidermal growth factor receptor-2 autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed