Compile Data Set for Download or QSAR
maximum 50k data
Found 23 Enz. Inhib. hit(s) with all data for entry = 50012465
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50:  15nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119113(1-{3-[N'-(3-Methoxy-4-oxazol-5-yl-phenyl)-N''-cyan...)
Affinity DataIC50:  16nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119045(1-(3-Methoxy-4-oxazol-5-yl-phenyl)-3-m-tolyl-urea ...)
Affinity DataIC50:  19nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119128(CHEMBL98265 | {3-[N'-(3-Methoxy-4-oxazol-5-yl-phen...)
Affinity DataIC50:  110nMAssay Description:The compound was tested for it's in vitro inhibitor potency against inosine monophosphate dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119120(CHEMBL101941 | N-Butyl-3-[N'-(3-methoxy-4-oxazol-5...)
Affinity DataIC50:  130nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119127(1-{3-[N'-(3-Methoxy-4-oxazol-5-yl-phenyl)-N''-cyan...)
Affinity DataIC50:  180nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119119(CHEMBL98740 | N''-cyano-N-[3-methoxy-4-(1,3-oxazol...)
Affinity DataIC50:  240nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119130(CHEMBL60730 | N''-cyano-N-[3-methoxy-4-(1,3-oxazol...)
Affinity DataIC50:  250nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119126(CHEMBL99625 | N''-cyano-N-[3-(hydroxymethyl)phenyl...)
Affinity DataIC50:  280nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119115(CHEMBL101822 | N''-cyano-N-[3-methoxy-4-(1,3-oxazo...)
Affinity DataIC50:  320nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119114(CHEMBL98393 | N''-cyano-N-[3-methoxy-4-(1,3-oxazol...)
Affinity DataIC50:  330nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119121(CHEMBL98322 | N''-cyano-N-[3-methoxy-4-(1,3-oxazol...)
Affinity DataIC50:  340nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119124(CHEMBL101463 | {3-[N'-(3-Methoxy-4-oxazol-5-yl-phe...)
Affinity DataIC50:  340nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119110(CHEMBL99278 | N-(3-Methoxy-4-oxazol-5-yl-phenyl)-N...)
Affinity DataIC50:  380nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119111(CHEMBL98904 | N''-methoxy-N-[3-methoxy-4-(1,3-oxaz...)
Affinity DataIC50:  660nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119129(CHEMBL317497 | ethyl(1E)-[(3-methoxy-4-oxazole-5-y...)
Affinity DataIC50:  740nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119123(CHEMBL329714 | N-Benzoyl-N'-(3-methoxy-4-oxazol-5-...)
Affinity DataIC50:  800nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119118(CHEMBL98225 | N-Acetyl-N'-(3-methoxy-4-oxazol-5-yl...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119125(CHEMBL98500 | N''-cyano-N-[3-methoxy-4-(1,3-oxazol...)
Affinity DataIC50:  1.10E+3nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119112(CHEMBL98700 | N''-cyano-N-[3-methoxy-4-(1,3-oxazol...)
Affinity DataIC50:  1.50E+3nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119122(CHEMBL316946 | N''-cyano-N-[3-methoxy-4-(1,3-oxazo...)
Affinity DataIC50:  2.20E+3nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119117(CHEMBL98215 | N-(3-Methoxy-4-oxazol-5-yl-phenyl)-N...)
Affinity DataIC50: >3.00E+3nMAssay Description:The compound was tested for it's in vitro inhibitor potency against inosine monophosphate dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119116(CHEMBL318413 | N-(3-Methoxy-4-oxazol-5-yl-phenyl)-...)
Affinity DataIC50: >3.00E+3nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed