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Found 8 Enz. Inhib. hit(s) with all data for entry = 50012728
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50122013(8-Chloro-5-oxy-benzo[e]pyrazolo[5,1-c][1,2,4]triaz...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-Ro-15-1788 from rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50078032(8-Chloro-3-thiophen-3-yl-benzo[e]pyrazolo[5,1-c][1...)
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H]-Ro-15-1788 from rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50122013(8-Chloro-5-oxy-benzo[e]pyrazolo[5,1-c][1,2,4]triaz...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-Ro-15-1788 from rat GABA-A receptor alpha3-beta2-gamma2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataKi:  13.9nMAssay Description:Displacement of [3H]-Ro-15-1788 from rat GABA-A receptor alpha3-beta2-gamma2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]-Ro-15-1788 from rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)
Affinity DataKi:  26.7nMAssay Description:Displacement of [3H]-Ro-15-1788 from rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50078032(8-Chloro-3-thiophen-3-yl-benzo[e]pyrazolo[5,1-c][1...)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]-Ro-15-1788 from rat GABA-A receptor alpha3-beta2-gamma2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)
Affinity DataKi:  383nMAssay Description:Displacement of [3H]-Ro-15-1788 from rat GABA-A receptor alpha3-beta2-gamma2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair