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Found 6 Enz. Inhib. hit(s) with all data for entry = 1253
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Weizmann Institute Of Science

LigandPNGBDBM10439((5S)-5-[(10-{[(5S)-2-oxo-1,2,5,6,7,8-hexahydroquin...)
Affinity DataKi:  0.800nM ΔG°:  -51.4kJ/mole IC50:  2.40nMpH: 7.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Weizmann Institute Of Science

LigandPNGBDBM10440((5S)-5-[(12-{[(5S)-2-oxo-1,2,5,6,7,8-hexahydroquin...)
Affinity DataKi:  4.5nM ΔG°:  -47.2kJ/mole IC50:  16nMpH: 7.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute Of Science

LigandPNGBDBM10440((5S)-5-[(12-{[(5S)-2-oxo-1,2,5,6,7,8-hexahydroquin...)
Affinity DataKi:  19.6nM ΔG°:  -43.6kJ/mole IC50:  52nMpH: 7.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute Of Science

LigandPNGBDBM10441((+)-Huperzine A | (+/-)Huperzine A | (-)-Huperzine...)
Affinity DataKi:  47.1nM ΔG°:  -41.4kJ/mole IC50:  114nMpH: 7.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Weizmann Institute Of Science

LigandPNGBDBM10441((+)-Huperzine A | (+/-)Huperzine A | (-)-Huperzine...)
Affinity DataKi:  175nM ΔG°:  -38.2kJ/mole IC50:  414nMpH: 7.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute Of Science

LigandPNGBDBM10439((5S)-5-[(10-{[(5S)-2-oxo-1,2,5,6,7,8-hexahydroquin...)
Affinity DataIC50:  151nMpH: 7.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed