Compile Data Set for Download or QSAR
maximum 50k data
Found 66 Enz. Inhib. hit(s) with all data for entry = 50012889
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123880((4-Chloro-phenyl)-(2-chloro-pyridine-4-carbonyl)-t...)
Affinity DataIC50:  2.00E+3nMAssay Description:Activity of selected HIV-1 N-acylthiocarbamates in enzyme assay against Virion-Associated reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123871((4-Chloro-phenyl)-(furan-2-carbonyl)-thiocarbamic ...)
Affinity DataIC50:  2.30E+3nMAssay Description:Activity of selected HIV-1 N-acylthiocarbamates in enzyme assay against Virion-Associated reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123875((4-Chloro-phenyl)-(thiophene-2-carbonyl)-thiocarba...)
Affinity DataIC50:  2.50E+3nMAssay Description:Activity of selected HIV-1 N-acylthiocarbamates in enzyme assay against Virion-Associated reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM1866(3-(5-bromopyridin-2-yl)-1-[2-(pyridin-2-yl)ethyl]t...)
Affinity DataIC50:  4.20E+3nMAssay Description:Activity of selected HIV-1 N-acylthiocarbamates in enzyme assay against Virion-Associated reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM1434(11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...)
Affinity DataIC50:  6.00E+3nMAssay Description:Activity of selected HIV-1 N-acylthiocarbamates in enzyme assay against Virion-Associated reverse transcriptaseMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123872((2-Phenoxy-acetyl)-phenyl-thiocarbamic acid O-(1-m...)
Affinity DataEC50:  1.40E+3nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123870(Benzoyl-phenyl-thiocarbamic acid O-[2-(1,3-dioxo-1...)
Affinity DataEC50:  400nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123917((4-Fluoro-phenyl)-(thiophene-2-carbonyl)-thiocarba...)
Affinity DataEC50:  100nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123881((4-Ethyl-phenyl)-(furan-2-carbonyl)-thiocarbamic a...)
Affinity DataEC50:  30nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123890(CHEMBL166333 | O-(1-methyl-2-phenoxyethyl) O-pheny...)
Affinity DataEC50: >2.00E+5nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123895(Benzoyl-phenyl-thiocarbamic acid O-phenethyl ester...)
Affinity DataEC50:  4.20E+3nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123916(CHEMBL349827 | Phenyl-(thiophene-2-carbonyl)-thioc...)
Affinity DataEC50:  2.00E+3nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123900((Naphthalene-2-carbonyl)-phenyl-thiocarbamic acid ...)
Affinity DataEC50:  6.00E+3nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123921((3-Nitro-benzoyl)-phenyl-thiocarbamic acid O-(1-me...)
Affinity DataEC50:  3.60E+3nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123886((Thiophene-2-carbonyl)-(3-trifluoromethyl-phenyl)-...)
Affinity DataEC50:  1.10E+4nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123888((2-Ethyl-phenyl)-(thiophene-2-carbonyl)-thiocarbam...)
Affinity DataEC50:  1.10E+4nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123906((3-Chloro-phenyl)-(thiophene-2-carbonyl)-thiocarba...)
Affinity DataEC50:  6.00E+3nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123877(Benzoyl-phenyl-thiocarbamic acid O-furan-2-ylmethy...)
Affinity DataEC50: >3.83E+4nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123868((4-Methyl-benzoyl)-phenyl-thiocarbamic acid O-(2-p...)
Affinity DataEC50:  9.90E+3nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123924((3-Acetyl-phenyl)-(thiophene-2-carbonyl)-thiocarba...)
Affinity DataEC50:  6.00E+3nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123909((3-Fluoro-phenyl)-(thiophene-2-carbonyl)-thiocarba...)
Affinity DataEC50:  1.10E+4nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM1866(3-(5-bromopyridin-2-yl)-1-[2-(pyridin-2-yl)ethyl]t...)
Affinity DataEC50:  20nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123883((Thiophene-2-carbonyl)-p-tolyl-thiocarbamic acid O...)
Affinity DataEC50:  400nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123889(CHEMBL164697 | Phenyl-(tetrahydro-furan-2-carbonyl...)
Affinity DataEC50:  5.80E+4nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123905((3-Nitro-phenyl)-(thiophene-2-carbonyl)-thiocarbam...)
Affinity DataEC50:  380nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123925((Thiophene-2-carbonyl)-m-tolyl-thiocarbamic acid O...)
Affinity DataEC50:  1.00E+4nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123914((2-Phenoxy-acetyl)-phenyl-thiocarbamic acid O-(2-p...)
Affinity DataEC50:  6.00E+3nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123923(CHEMBL164503 | Phenyl-(3,4,5-trimethoxy-benzoyl)-t...)
Affinity DataEC50:  9.60E+3nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123878((4-Chloro-3-nitro-benzoyl)-phenyl-thiocarbamic aci...)
Affinity DataEC50:  7.60E+3nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123875((4-Chloro-phenyl)-(thiophene-2-carbonyl)-thiocarba...)
Affinity DataEC50:  8nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123892((3-Methoxy-phenyl)-(thiophene-2-carbonyl)-thiocarb...)
Affinity DataEC50:  3.50E+3nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123893((3-Bromo-phenyl)-(thiophene-2-carbonyl)-thiocarbam...)
Affinity DataEC50:  1.20E+3nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123918((4-Chloro-benzoyl)-phenyl-thiocarbamic acid O-(2-p...)
Affinity DataEC50:  1.03E+4nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123896((4-Chloro-benzoyl)-(4-chloro-phenyl)-thiocarbamic ...)
Affinity DataEC50:  25nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123904((3,5-Dichloro-benzoyl)-phenyl-thiocarbamic acid O-...)
Affinity DataEC50:  8.80E+3nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123867(Benzoyl-(4-bromo-phenyl)-thiocarbamic acid O-[2-(1...)
Affinity DataEC50:  35nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123879(Benzoyl-phenyl-thiocarbamic acid O-(2-phenylsulfan...)
Affinity DataEC50: >4.40E+4nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123885(Benzoyl-(4-fluoro-phenyl)-thiocarbamic acid O-(2-p...)
Affinity DataEC50:  4.00E+3nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123912((4-Nitro-phenyl)-(thiophene-2-carbonyl)-thiocarbam...)
Affinity DataEC50:  6.00E+3nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123897((3-Chloro-phenyl)-(thiophene-2-carbonyl)-thiocarba...)
Affinity DataEC50:  1.10E+4nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123884((Furan-2-carbonyl)-phenyl-thiocarbamic acid O-phen...)
Affinity DataEC50:  4.30E+3nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123894(CHEMBL165288 | Phenyl-(3-phenyl-acryloyl)-thiocarb...)
Affinity DataEC50:  4.50E+3nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123898((2,4-Dichloro-benzoyl)-phenyl-thiocarbamic acid O-...)
Affinity DataEC50:  1.16E+4nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123901(CHEMBL351212 | O-butyl O-(1-methyl-2-phenoxyethyl)...)
Affinity DataEC50:  4.70E+4nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123880((4-Chloro-phenyl)-(2-chloro-pyridine-4-carbonyl)-t...)
Affinity DataEC50:  5nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123882(Benzoyl-(4-chloro-phenyl)-thiocarbamic acid O-[2-(...)
Affinity DataEC50:  100nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123903(CHEMBL168044 | O-(1-methyl-2-phenoxyethyl) O-propy...)
Affinity DataEC50:  1.31E+5nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123871((4-Chloro-phenyl)-(furan-2-carbonyl)-thiocarbamic ...)
Affinity DataEC50:  7nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123911((4-Chloro-benzoyl)-phenyl-thiocarbamic acid O-phen...)
Affinity DataEC50:  4.00E+3nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50123887(Benzoyl-cyclohexyl-thiocarbamic acid O-(2-phenoxy-...)
Affinity DataEC50:  2.00E+5nMAssay Description:Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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