Compile Data Set for Download or QSAR
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Found 37 Enz. Inhib. hit(s) with all data for entry = 50012901
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124048(2-((R)-3-{(S)-8-Methyl-4-oxo-3-(3-trifluoromethyl-...)
Affinity DataIC50:  80nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124044((S)-8-Methyl-8-[(3-methylsulfanyl-phenylcarbamoyl)...)
Affinity DataIC50:  90nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124056(2-((S)-2-{(S)-8-Methyl-4-oxo-3-(3-trifluoromethyl-...)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124063(2-((R)-3-{(S)-8-Methyl-4-oxo-3-(3-trifluoromethyl-...)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124055((S)-8-Methyl-8-[(R)-3-(3-methylsulfanyl-phenyl)-ur...)
Affinity DataIC50:  130nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124049((S)-8-[(2-Carbamoyl-phenylcarbamoyl)-methyl]-8-met...)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124039((S)-8-[(R)-3-(2-Ethoxy-phenyl)-ureido]-8-methyl-4-...)
Affinity DataIC50:  160nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124035((S)-8-Methyl-4-oxo-8-((S)-phenylcarbamoylmethyl)-3...)
Affinity DataIC50:  170nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124042((S)-8-Methyl-8-((S)-naphthalen-1-ylcarbamoylmethyl...)
Affinity DataIC50:  170nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124057((S)-8-Methyl-8-[(R)-3-(2-nitro-phenyl)-ureido]-4-o...)
Affinity DataIC50:  180nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124034((S)-8-Methyl-8-[(2-methylcarbamoyl-phenylcarbamoyl...)
Affinity DataIC50:  180nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124038((S)-8-[(2-Methoxy-phenylcarbamoyl)-methyl]-8-methy...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124053((S)-8-Methyl-8-((R)-3-naphthalen-1-yl-ureido)-4-ox...)
Affinity DataIC50:  270nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124043((S)-8-Methyl-4-oxo-8-[(R)-3-(2-phenoxy-phenyl)-ure...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124036((S)-8-[(R)-3-(2-Methoxy-phenyl)-ureido]-8-methyl-4...)
Affinity DataIC50:  360nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124040((S)-8-[(R)-3-(2-Chloro-phenyl)-ureido]-8-methyl-4-...)
Affinity DataIC50:  370nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124033((S)-8-((S)-Isoquinolin-1-ylcarbamoylmethyl)-8-meth...)
Affinity DataIC50:  440nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124062((S)-8-[(R)-3-(3-Fluoro-phenyl)-ureido]-8-methyl-4-...)
Affinity DataIC50:  500nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124066((S)-8-Methyl-8-[(R)-3-(2-methylsulfanyl-phenyl)-ur...)
Affinity DataIC50:  710nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124046((S)-8-Methyl-4-oxo-8-((R)-3-o-tolyl-ureido)-3-(3-t...)
Affinity DataIC50:  780nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124052((S)-8-Methyl-4-oxo-8-((R)-3-phenyl-ureido)-3-(3-tr...)
Affinity DataIC50:  790nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124058((S)-8-[(R)-3-(4-Fluoro-phenyl)-ureido]-8-methyl-4-...)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124067(4-((R)-3-{(S)-8-Methyl-4-oxo-3-(3-trifluoromethyl-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124069((S)-8-[(R)-3-(4-Chloro-phenyl)-ureido]-8-methyl-4-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124047((S)-8-((R)-3-Benzyl-ureido)-8-methyl-4-oxo-3-(3-tr...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124061(CHEMBL164441 | {(S)-8-Methyl-4-oxo-3-(3-trifluorom...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124045((S)-8-Methyl-8-[(2-dimethylcarbamoyl-phenylcarbamo...)
Affinity DataIC50:  1.46E+3nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124041(3-((R)-3-{(S)-8-Methyl-4-oxo-3-(3-trifluoromethyl-...)
Affinity DataIC50:  1.55E+3nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124050(3-((R)-3-{(S)-8-Methyl-4-oxo-3-(3-trifluoromethyl-...)
Affinity DataIC50:  1.77E+3nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124054((S)-8-Methyl-8-[(R)-3-(4-methylsulfanyl-phenyl)-ur...)
Affinity DataIC50:  2.36E+3nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124059((S)-8-Methyl-4-oxo-8-((R)-phenylacetylamino)-3-(3-...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124037((S)-8-Methyl-8-[(2-nitro-phenylcarbamoyl)-methyl]-...)
Affinity DataIC50:  2.53E+3nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124051((S)-8-((R)-Benzoylamino)-8-methyl-4-oxo-3-(3-trifl...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124068((S)-8-Methyl-4-oxo-8-[(R)-3-(4-phenoxy-phenyl)-ure...)
Affinity DataIC50:  4.74E+3nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124065(2-((R)-3-{(S)-8-Methyl-4-oxo-3-(3-trifluoromethyl-...)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124064((S)-4-Oxo-3-(3-trifluoromethyl-benzylamino)-4,6,7,...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124060((S)-8-((R)-3-Biphenyl-2-yl-ureido)-8-methyl-4-oxo-...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed