Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with all data for entry = 1761
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13954(3-({5-[(2S)-3-{4-[(2-carboxyphenyl)amidoformic aci...)
Affinity DataKi:  22nM ΔG°:  -43.3kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13954(3-({5-[(2S)-3-{4-[(2-carboxyphenyl)amidoformic aci...)
Affinity DataKi:  49nM ΔG°:  -41.3kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13953(1:1 racemic mixture | 2-({4-[2-acetamido-2-(pentyl...)
Affinity DataKi:  1.10E+3nM ΔG°:  -33.7kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13953(1:1 racemic mixture | 2-({4-[2-acetamido-2-(pentyl...)
Affinity DataKi:  1.10E+3nM ΔG°:  -33.7kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13952(2-(Naphthalen-1-yloxalylamino)benzoic Acid | 2-(na...)
Affinity DataKi:  3.90E+4nM ΔG°:  -24.9kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13952(2-(Naphthalen-1-yloxalylamino)benzoic Acid | 2-(na...)
Affinity DataKi:  4.40E+4nM ΔG°:  -24.6kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13951(2-[(2,3-Dimethylphenyl)oxalylamino]benzoic acid | ...)
Affinity DataKi:  1.64E+5nM ΔG°:  -21.4kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13951(2-[(2,3-Dimethylphenyl)oxalylamino]benzoic acid | ...)
Affinity DataKi:  2.93E+5nM ΔG°:  -20.0kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed