Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with all data for entry = 50000209
TargetLanosterol synthase(Rattus norvegicus)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50003025(1-((4aS,5S,6S,8aS)-6-Hydroxy-5,8a-dimethyl-octahyd...)
Affinity DataIC50:  110nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50003026(1-(6-Hydroxy-5,8a-dimethyl-octahydro-isoquinolin-2...)
Affinity DataIC50:  210nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50003032((4aS,5S,6S,8aS)-2-Dodecyl-5,8a-dimethyl-decahydro-...)
Affinity DataIC50:  550nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50003027((4aS,5S,6S,8aS)-5,8a-Dimethyl-2-(1,5,9-trimethyl-d...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50003030((2S,4aS,8aR)-1,1,4a-Trimethyl-decahydro-naphthalen...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50003028(2-(Dodecane-1-sulfinyl)-5,8a-dimethyl-decahydro-is...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50003031(1-(6-Hydroxy-5,8a-dimethyl-octahydro-isoquinolin-2...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50003029(2-(Dodecane-1-sulfonyl)-5,8a-dimethyl-decahydro-is...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed