Compile Data Set for Download or QSAR
maximum 50k data
Found 21 Enz. Inhib. hit(s) with all data for entry = 1980
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15773((2S)-1-({4-[3-(4-fluorophenyl)-1H-pyrrolo[3,2-b]py...)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15774((2R)-1-({4-[3-(4-fluorophenyl)-1H-pyrrolo[3,2-b]py...)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15775(1-({4-[3-(4-fluorophenyl)-1H-pyrrolo[3,2-b]pyridin...)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15776(2-({4-[3-(4-fluorophenyl)-1H-pyrrolo[3,2-b]pyridin...)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15772(4-({4-[3-(4-fluorophenyl)-1H-pyrrolo[3,2-b]pyridin...)
Affinity DataIC50:  5nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15756(3-(4-Fluorophenyl)-2-(pyridin-4-yl)-1H-pyrrolo[3,2...)
Affinity DataIC50:  6.5nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15764(3-(4-Fluorophenyl)-1-methoxy-ethyl-2-pyridin-4-yl-...)
Affinity DataIC50:  21nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15765(3-(4-Fluorophenyl)-1-ethyl-2-pyridin-4-yl-1H-pyrro...)
Affinity DataIC50:  24nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15759(4,7 Diazaindole 22 | 4-[7-(4-fluorophenyl)-5H-pyrr...)
Affinity DataIC50:  53nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15763(3-(4-Fluoro-phenyl)-1-methoxy-2-pyridin-4-yl-1H-py...)
Affinity DataIC50:  68nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15762(3-(4-Fluorophenyl-2-(pyridin-4yl)furo[3,2-b]pyridi...)
Affinity DataIC50:  86nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15766(3-(4-Fluorophenyl)-1-methyl-2-pyridin-4-yl-1H-pyrr...)
Affinity DataIC50:  98nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15767(1-[3-(4-fluorophenyl)-2-(pyridin-4-yl)-1H-pyrrolo[...)
Affinity DataIC50:  172nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15768(3-(4-Fluorophenyl)-1-morpholinoethyl-2-pyridin-4-y...)
Affinity DataIC50:  185nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15769(3-(4-Fluorophenyl)-1-pyrrolidinoethyl-2-pyridin-4-...)
Affinity DataIC50:  217nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15760(4,6 Diazaindole 24 | 4-[7-(4-fluorophenyl)-5H-pyrr...)
Affinity DataIC50:  895nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15758(3-(4-Fluorophenyl)-2-pyridin-4-yl-1H-indole | 3-(4...)
Affinity DataIC50:  1.80E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15770(3-(4-Fluorophenyl)-1-piperidinoethyl-2-pyridin-4-y...)
Affinity DataIC50:  1.97E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15757(3-(4-Fluorophenyl)-2-pyridin-4-yl)-1H-pyrrolo[3,2-...)
Affinity DataIC50:  3.10E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15761(7-(4-Fluoro-phenyl)-6-pyridin-4-yl-7H-pyrrolo[2,3-...)
Affinity DataIC50:  3.30E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15771(2-[3-(4-fluorophenyl)-2-(pyridin-4-yl)-1H-pyrrolo[...)
Affinity DataIC50:  2.36E+4nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed