Compile Data Set for Download or QSAR
maximum 50k data
Found 10 Enz. Inhib. hit(s) with all data for entry = 50013871
Target72 kDa type IV collagenase(Homo sapiens (Human))
Umr/Cnrs 6013

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)
Affinity DataIC50:  0.104nMAssay Description:Inhibition of human matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Umr/Cnrs 6013

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)
Affinity DataIC50:  0.191nMAssay Description:Inhibition of human matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Umr/Cnrs 6013

Curated by ChEMBL
LigandPNGBDBM50135601((S,E)-N1-(3-(1H-indol-3-yl)-1-(methylamino)-1-oxop...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Umr/Cnrs 6013

Curated by ChEMBL
LigandPNGBDBM50135602(CHEMBL420259 | N*1*-{2-[2-(2-Dimethylamino-ethyl)-...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of human matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Umr/Cnrs 6013

Curated by ChEMBL
LigandPNGBDBM50135600((S)-2-((E)-2-Hydroxycarbamoylmethyl-4-methyl-pent-...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Umr/Cnrs 6013

Curated by ChEMBL
LigandPNGBDBM50451552(CHEMBL2111573)
Affinity DataIC50:  20nMAssay Description:Inhibition of human matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Umr/Cnrs 6013

Curated by ChEMBL
LigandPNGBDBM50135601((S,E)-N1-(3-(1H-indol-3-yl)-1-(methylamino)-1-oxop...)
Affinity DataIC50:  179nMAssay Description:Inhibition of PKD2 ( assessed as residual activity at 1 uM ) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Umr/Cnrs 6013

Curated by ChEMBL
LigandPNGBDBM50135602(CHEMBL420259 | N*1*-{2-[2-(2-Dimethylamino-ethyl)-...)
Affinity DataIC50:  665nMAssay Description:Inhibition of human matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Umr/Cnrs 6013

Curated by ChEMBL
LigandPNGBDBM50451552(CHEMBL2111573)
Affinity DataIC50:  910nMAssay Description:Inhibition of human matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Umr/Cnrs 6013

Curated by ChEMBL
LigandPNGBDBM50135600((S)-2-((E)-2-Hydroxycarbamoylmethyl-4-methyl-pent-...)
Affinity DataIC50:  2.34E+3nMAssay Description:Inhibition of human matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed