Compile Data Set for Download or QSAR
maximum 50k data
Found 65 Enz. Inhib. hit(s) with all data for entry = 50035346
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136591(3-[(3R,4R)-3,4-Dimethyl-1-(3,5,5-trimethyl-hexyl)-...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136599(3-[(3R,4R)-3,4-Dimethyl-1-(4-methylsulfanyl-benzyl...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50045767((+)-N-phenethyl trans-3(R),4(R)-dimethyl-4-(3-hydr...)
Affinity DataKi:  1.90nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136600(3-[(3R,4R)-3,4-Dimethyl-1-(3-phenyl-propyl)-piperi...)
Affinity DataKi:  3.10nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136603(3-[(3R,4R)-1-(4-tert-Butyl-benzyl)-3,4-dimethyl-pi...)
Affinity DataKi:  3.20nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataKi:  3.70nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136597(3-((3R,4R)-3,4-Dimethyl-1-phenethyl-piperidin-4-yl...)
Affinity DataKi:  4.70nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136596(3-[(3R,4R)-3,4-Dimethyl-1-(3-phenyl-butyl)-piperid...)
Affinity DataKi:  5nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136588(3-[(3R,4R)-1-(4-Dimethylamino-benzyl)-3,4-dimethyl...)
Affinity DataKi:  5.30nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136591(3-[(3R,4R)-3,4-Dimethyl-1-(3,5,5-trimethyl-hexyl)-...)
Affinity DataKi:  5.40nMAssay Description:Binding affinity at cloned human kappa opioid receptor by [3H]diprenorphine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136598(3-[(3R,4R)-1-(4-Methoxy-benzyl)-3,4-dimethyl-piper...)
Affinity DataKi:  5.5nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136592(3-((3R,4R)-1-Benzofuran-2-ylmethyl-3,4-dimethyl-pi...)
Affinity DataKi:  6.20nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136587(3-((3R,4R)-3,4-Dimethyl-1-quinolin-2-ylmethyl-pipe...)
Affinity DataKi:  8nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136584(3-[(3R,4R)-1-(1-Benzenesulfonyl-1H-pyrrol-2-ylmeth...)
Affinity DataKi:  8.30nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136583(3-[(3R,4R)-1-(2,4-Dimethoxy-benzyl)-3,4-dimethyl-p...)
Affinity DataKi:  8.80nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataKi:  9.20nMAssay Description:Binding affinity at cloned human kappa opioid receptor by [3H]diprenorphine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136593(3-[(3R,4R)-1-(3-Chloro-benzyl)-3,4-dimethyl-piperi...)
Affinity DataKi:  9.70nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136604(CHEMBL138036 | [3-((3R,4R)-3,4-Dimethyl-1-phenethy...)
Affinity DataKi:  11nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136606(3-[(3R,4R)-1-(3,5-Dimethyl-1-phenyl-1H-pyrazol-4-y...)
Affinity DataKi:  13nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136591(3-[(3R,4R)-3,4-Dimethyl-1-(3,5,5-trimethyl-hexyl)-...)
Affinity DataKi:  14nMAssay Description:Concentration required to inhibit the binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136602(3-[(3R,4R)-1-(3-Methoxy-benzyl)-3,4-dimethyl-piper...)
Affinity DataKi:  15nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136601(3-((3R,4R)-1-Benzyl-3,4-dimethyl-piperidin-4-yl)-b...)
Affinity DataKi:  16nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50045767((+)-N-phenethyl trans-3(R),4(R)-dimethyl-4-(3-hydr...)
Affinity DataKi:  17nMAssay Description:Binding affinity at cloned human kappa opioid receptor by [3H]diprenorphine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136589(3-[(3R,4R)-1-(3-Hydroxy-benzyl)-3,4-dimethyl-piper...)
Affinity DataKi:  29nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataKi:  33nMAssay Description:Concentration required to inhibit the binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50045767((+)-N-phenethyl trans-3(R),4(R)-dimethyl-4-(3-hydr...)
Affinity DataKi:  33nMAssay Description:Concentration required to inhibit the binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136607(3-((3R,4R)-1-Cyclopropylmethyl-3,4-dimethyl-piperi...)
Affinity DataKi:  53nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136593(3-[(3R,4R)-1-(3-Chloro-benzyl)-3,4-dimethyl-piperi...)
Affinity DataKi:  57nMAssay Description:Inhibition of [3H]diprenorphine binding to the cloned human delta opioid receptors using 10 uM concentration of the compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136586(CHEMBL138750 | N-[3-((3R,4R)-3,4-Dimethyl-1-phenet...)
Affinity DataKi:  68nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136590(3-((3R,4R)-1-Cyclohexylmethyl-3,4-dimethyl-piperid...)
Affinity DataKi:  69nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136594(3-((3R,4R)-3,4-Dimethyl-1-phenethyl-piperidin-4-yl...)
Affinity DataKi:  71nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136597(3-((3R,4R)-3,4-Dimethyl-1-phenethyl-piperidin-4-yl...)
Affinity DataKi:  72nMAssay Description:Concentration required to inhibit the binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136600(3-[(3R,4R)-3,4-Dimethyl-1-(3-phenyl-propyl)-piperi...)
Affinity DataKi:  73nMAssay Description:Concentration required to inhibit the binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136597(3-((3R,4R)-3,4-Dimethyl-1-phenethyl-piperidin-4-yl...)
Affinity DataKi:  95nMAssay Description:Binding affinity at cloned human kappa opioid receptor by [3H]diprenorphine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136596(3-[(3R,4R)-3,4-Dimethyl-1-(3-phenyl-butyl)-piperid...)
Affinity DataKi:  100nMAssay Description:Binding affinity at cloned human kappa opioid receptor by [3H]diprenorphine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136599(3-[(3R,4R)-3,4-Dimethyl-1-(4-methylsulfanyl-benzyl...)
Affinity DataKi:  110nMAssay Description:Concentration required to inhibit the binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136603(3-[(3R,4R)-1-(4-tert-Butyl-benzyl)-3,4-dimethyl-pi...)
Affinity DataKi:  120nMAssay Description:Binding affinity at cloned human kappa opioid receptor by [3H]diprenorphine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136599(3-[(3R,4R)-3,4-Dimethyl-1-(4-methylsulfanyl-benzyl...)
Affinity DataKi:  120nMAssay Description:Binding affinity at cloned human kappa opioid receptor by [3H]diprenorphine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136589(3-[(3R,4R)-1-(3-Hydroxy-benzyl)-3,4-dimethyl-piper...)
Affinity DataKi:  140nMAssay Description:Binding affinity at cloned human kappa opioid receptor by [3H]diprenorphine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136607(3-((3R,4R)-1-Cyclopropylmethyl-3,4-dimethyl-piperi...)
Affinity DataKi:  140nMAssay Description:Binding affinity at cloned human kappa opioid receptor by [3H]diprenorphine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136600(3-[(3R,4R)-3,4-Dimethyl-1-(3-phenyl-propyl)-piperi...)
Affinity DataKi:  140nMAssay Description:Binding affinity at cloned human kappa opioid receptor by [3H]diprenorphine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136595(3-((3R,4R)-3,4-Dimethyl-1-phenethyl-piperidin-4-yl...)
Affinity DataKi:  150nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136593(3-[(3R,4R)-1-(3-Chloro-benzyl)-3,4-dimethyl-piperi...)
Affinity DataKi:  190nMAssay Description:Binding affinity at cloned human kappa opioid receptor by [3H]diprenorphine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136584(3-[(3R,4R)-1-(1-Benzenesulfonyl-1H-pyrrol-2-ylmeth...)
Affinity DataKi:  210nMAssay Description:Binding affinity at cloned human kappa opioid receptor by [3H]diprenorphine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136601(3-((3R,4R)-1-Benzyl-3,4-dimethyl-piperidin-4-yl)-b...)
Affinity DataKi:  210nMAssay Description:Binding affinity at cloned human kappa opioid receptor by [3H]diprenorphine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136587(3-((3R,4R)-3,4-Dimethyl-1-quinolin-2-ylmethyl-pipe...)
Affinity DataKi:  220nMAssay Description:Concentration required to inhibit the binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136598(3-[(3R,4R)-1-(4-Methoxy-benzyl)-3,4-dimethyl-piper...)
Affinity DataKi:  220nMAssay Description:Binding affinity at cloned human kappa opioid receptor by [3H]diprenorphine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136604(CHEMBL138036 | [3-((3R,4R)-3,4-Dimethyl-1-phenethy...)
Affinity DataKi:  270nMAssay Description:Concentration required to inhibit the binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136592(3-((3R,4R)-1-Benzofuran-2-ylmethyl-3,4-dimethyl-pi...)
Affinity DataKi:  300nMAssay Description:Binding affinity at cloned human kappa opioid receptor by [3H]diprenorphine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136596(3-[(3R,4R)-3,4-Dimethyl-1-(3-phenyl-butyl)-piperid...)
Affinity DataKi:  310nMAssay Description:Concentration required to inhibit the binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 65 total ) | Next | Last >>
Jump to: